42116-56-3 Usage
Description
tert-butyl 3-hydrazinyl-3-oxopropylcarbamate, also known as Boc-β-alanine hydrazide, is a chemical compound that serves as an intermediate in the synthesis of various organic compounds. It is characterized by its hydrazide group and a carbamate moiety, which contribute to its reactivity and potential applications in chemical and pharmaceutical processes.
Uses
Used in Pharmaceutical Industry:
tert-butyl 3-hydrazinyl-3-oxopropylcarbamate is used as a synthetic intermediate for the production of GABAA receptor agonists. These agonists are important in the treatment of various disorders, as they modulate the activity of the GABAA receptors, which play a crucial role in the central nervous system. The agonists help in managing conditions such as anxiety, insomnia, and epilepsy by enhancing the inhibitory effects of GABA in the brain.
Used in Chemical Synthesis:
In the field of organic chemistry, tert-butyl 3-hydrazinyl-3-oxopropylcarbamate is utilized as a building block for the synthesis of complex organic molecules. Its reactivity and functional groups make it a valuable component in the creation of pharmaceuticals, agrochemicals, and other specialty chemicals. The hydrazide group can participate in various chemical reactions, such as condensation, cyclization, and reduction, enabling the formation of diverse molecular structures with potential applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 42116-56-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,1,1 and 6 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 42116-56:
(7*4)+(6*2)+(5*1)+(4*1)+(3*6)+(2*5)+(1*6)=83
83 % 10 = 3
So 42116-56-3 is a valid CAS Registry Number.
42116-56-3Relevant articles and documents
Cascade reactions for constructing heterocycles containing a pyrimidino-pyrazino-pyrimidine core using 1,2,4-triazole scaffolds
Doroshchuk, Roman O.,García López, Jesús,Iegorov, Oleg A.,Khomenko, Dmytro M.,López Ortiz, Fernando,Lampeka, Rostyslav D.,Raspertova, Ilona V.,Shova, Sergiu
, (2019)
The regioselective cyclocondensation of aminoethyl-1,2,4-triazoles and glyoxal provides pentacyclic heterocycles in which two 7,8-dihydro-5H-6λ2-[1,2,4]triazolo[1,5-c]pyrimidine systems are connected through CH(OH) bridges generating a central piperazine-2,5-diol ring. The structure of the new compounds was elucidated based on 1H, 13C and 15N NMR spectroscopic methods. The molecular structure of the parent compound generated from aminoethyl-1,2,4-triazole was established by single crystal X-ray diffraction.
Synthesis of macrocycles containing 1,3,4-oxadiazole and pyridine moieties
Poojari, Subba,Naik, Parameshwar,Krishnamurthy
, p. 305 - 309 (2014/01/06)
A series of peptide-like 25-28 membered macrocycles containing 1,3,4-oxadiazoles and pyridines bearing a chiral center scaffold have been synthesized by using known coupling reagents and common protecting groups. The yield of the purified macrocycles was poor on an average, yet it seems to be independent of amino acid substitution or stereochemistry. These macrocycles represent a new class of structures for further development and for future application in high-throughput screening against a variety of biological targets.
TRIAZOLE DERIVATIVE
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, (2008/06/13)
A compound represented by the formula (I) below or a pharmaceutically acceptable salt thereof has an effect of inhibiting binding between SIP and its receptor Edg-1(S1P1), and is useful as a pharmaceutical product. [where A represents a sulfur
