42158-45-2Relevant articles and documents
4-Heterocyclyl tetrahydropyridines as selective ligands for the human dopamine D4 receptor.
Haworth,Harrison,Kulagowski,Leeson,Owens,Ridgill,Teall,Fielding,Chapman,Emms,Marwood,Patel,Moss
, p. 2211 - 2216 (1997)
A series of 1,2,3,6-tetrahydropyridines 3 were synthesised, which resulted in selective high affinity dopamine D4 ligands. The SAR of heterocyclic replacements and aromatic substitution was investigated, leading to compounds of nanomolar bindin