4218-48-8

Basic information

• Product Name: 1-ETHYL-4-ISO-PROPYLBENZENE
• Synonyms: 1-ETHYL-4-ISO-PROPYLBENZENE;BENZENE,1-ETHYLL-4-1-METHYL;1-Ethyl-4-(1-methylethyl)benzene;1-Isopropyl-4-ethylbenzene;4-Ethylcumene;1-ethyl-4-propan-2-ylbenzene;1-ethyl-4-propan-2-yl-benzene
• CAS NO: 4218-48-8
• Molecular Formula: C₁₁H₁₆
• Molecular Weight: 148.24474
• Mol File: 4218-48-8.mol
• Article Data: 10

Chemical Properties

• Melting Point: -44.72°C (estimate)
• Boiling Point: 196.6°C
• Flash Point: 65.7°C
• Appearance: /
• Density: 0.8546
• Vapor Pressure: 0.541mmHg at 25°C
• Refractive Index: 1.4900
• CAS DataBase Reference: 1-ETHYL-4-ISO-PROPYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ETHYL-4-ISO-PROPYLBENZENE(4218-48-8)
• EPA Substance Registry System: 1-ETHYL-4-ISO-PROPYLBENZENE(4218-48-8)

Safety Data

• Hazardous Substances Data: 4218-48-8(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Sweet

Uses

a. Production of fragrances
b. Solvent in manufacturing of paints and coatings

Occurrence

Found in small amounts in some essential oils

Environmental impact

Potential contaminant in groundwater

Health effects

a. Skin irritation
b. Eye irritation
c. Respiratory system irritation
d. Potential harmful effects on liver and kidneys

Safety precautions

Proper handling and storage to prevent adverse health effects

InChI:InChI=1/C11H16/c1-4-10-5-7-11(8-6-10)9(2)3/h5-9H,4H2,1-3H3

Upstream product

• 71-23-8 propan-1-ol 
• 100-41-4 ethylbenzene 
• 645-13-6 4-isopropylacetophenone 
• 106-94-5 propyl bromide 
• 75-26-3 isopropyl bromide 
• 99-87-6 4-methylisopropylbenzene 
• 22722-98-1 sodium bis(2-methoxyethoxy)aluminum hydride 
• 73371-45-6 2-ethyl-6,6-dimethylbicyclo(3.1.1)hept-2-ene 
• 187737-37-7 propene 
• 425-75-2 trifluoromethanesulfonic acid ethyl ester 
• 128-50-7 nopol 
• 74892-00-5 6,6-dimethyl-2-(p-tolylsulphonylethyl)bicyclo<3.1.1>hept-2-ene 
• 117858-85-2 (1S,2S,3S,5R)-2-(2-Hydroxy-ethyl)-6,6-dimethyl-bicyclo[3.1.1]heptan-3-ol 
• 7637-07-2 boron trifluoride 

Downstream Products

• 5464-00-6 [1-(4-ethyl-phenyl)-1-methyl-ethyl]-succinic acid 
• 114841-66-6 4-(4-ethyl-phenyl)-[1,2]dithiol-3-thione 
• 1130-58-1 1-(1,1-Dimethylpropyl)-4-ethylbenzol 
• 27702-09-6 1-sec-butyl-4-isopropyl-benzene 
• 17797-07-8 p-(2-Aminoprop-2-yl)-ethylbenzol 
• 1475-10-1 1-(4-isopropylphenyl)ethanol 
• 36207-14-4 4-ethylcumyl alcohol 
• 645-13-6 4-isopropylacetophenone 
• 85-22-3 2,3,4,5,6-pentabromo-1-ethylbenzene 
• 1314905-79-7 (E)-4-(2-ethyl-5-isopropylphenyl)-4-oxo-2-butenoic acid 
• 5702-74-9 N-(4-iso-propylphenyl)acetamide 
• 3663-34-1 N-(4-ethylphenyl)acetamide 
• 937-30-4 4-ethylacetophenone 

Relevant articles and documents

Intermolecular Radical C(sp3)?H Amination under Iodine Catalysis

The direct amination of aliphatic C?H bonds has remained one of the most tantalizing transformations in organic chemistry. Herein, we report on a unique catalyst system, which enables the elusive intermolecular C(sp3)?H amination. This practical synthetic strategy provides access to aminated building blocks and fosters innovative multiple C?H amination within a new approach to aminated heterocycles. The synthetic utility is demonstrated by the synthesis of four relevant pharmaceuticals.

Isopropylation of ethyl benzene using MCM-41 and metals substituted MCM-41

Mesoporous MCM-41, Al-MCM-41, Fe-MCM-41, Mg-MCM-41 and Mn-MCM-41 were synthesized by hydrothermal process for catalytic applications. Tetradecyl trimethyl ammonium bromide was used as the structure directing template. Sodium silicate and salts of aluminium, iron, magnesium and manganese were the sources of silicon, aluminium, iron, magnesium and manganese, respectively. All the synthesised materials were characterised by BET, XRD and FTIR techniques. The XRD patterns of all the samples showed an intense signal at an angle of about 2?; (2θ) due to (100) plane of hexagonal mesophase. The patterns due to other planes were less intense. BET surface area of all the materials were in the range from 772-1273 m2/g and the pore diameter varies from 2.546- 2.663 nm. The catalytic performance of these materials has been tested for isopropylation of ethyl benzene. The influence of temperature, feed ratio and weight hourly space velocity (WHSV) were studied for all the aforesaid reactions for maximum conversion and product selectivity. In addition to p-isopropylethylbenzene, a commercially valuable compound diisopropyl ether was also obtained from isopropyl alcohol.