4222-08-6

Basic information

• Product Name: 2,2-Diphenyl-2H-1-benzopyran
• Synonyms: 2,2-Diphenyl-2H-1-benzopyran
• CAS NO: 4222-08-6
• Molecular Formula: C₂₁H₁₆O
• Molecular Weight: 284.35
• Mol File: 4222-08-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 428.4°C at 760 mmHg
• Flash Point: 212.3°C
• Appearance: /
• Density: 1.149g/cm³
• Vapor Pressure: 3.81E-07mmHg at 25°C
• Refractive Index: 1.633
• CAS DataBase Reference: 2,2-Diphenyl-2H-1-benzopyran(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-Diphenyl-2H-1-benzopyran(4222-08-6)
• EPA Substance Registry System: 2,2-Diphenyl-2H-1-benzopyran(4222-08-6)

Safety Data

• Hazardous Substances Data: 4222-08-6(Hazardous Substances Data)

Usage

General Description

2,2-Diphenyl-2H-1-benzopyran, also known as benzofuran, is a chemical compound containing a benzene ring fused to a furan ring. It is a colorless solid with a sweet, floral odor, and it is used in the production of various pharmaceuticals and fragrances. Benzofuran is also a precursor to a range of other chemical substances, including dyes, agricultural chemicals, and insecticides. Studies have shown that benzofuran exhibits anti-inflammatory, antioxidant, and anticancer properties, making it a potentially valuable compound for medicinal applications. However,

InChI:InChI=1/C21H16O/c1-3-10-18(11-4-1)21(19-12-5-2-6-13-19)16-15-17-9-7-8-14-20(17)22-21/h1-16H

Upstream product

• 4222-10-0 3-(2-hydroxy-phenyl)-1,1-diphenyl-allyl alcohol 
• 3923-52-2 1,1-diphenyl-2-propyn-1-ol 
• 108-95-2 phenol 
• 1210-39-5 3,3-diphenyl-2-propenal 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 22825-21-4 3,3-diphenylcyclopropene 
• 5661-50-7 N-(phenoxy)acetamide 
• 343309-52-4 2-(3-hydroxy-3,3-diphenylprop-1-yn-1-yl)phenol 
• 1666-14-4 N’-(2-hydroxybenzylidene)-4-methylbenzene-1-sulfonohydrazide 
• 24892-82-8 1-bromo-2-(1-phenylpropen-1-yl)benzene 
• 90-02-8 salicylaldehyde 

Downstream Products

• 36839-06-2 2-(1-Methoxy-3,3-diphenyl-allyl)-phenol 
• 1041641-32-0 C₂₆H₂₇NO 
• 1041641-31-9 1,1-diphenyl-3-(2-hydroxyphenyl)-3-morpholino-1-propene 
• 1041641-34-2 C₂₄H₂₅NO 
• 1041641-36-4 C₂₃H₂₃NO₂ 

Relevant articles and documents

Rhodium(III)-catalyzed transannulation of cyclopropenes with n-phenoxyacetamides through C-H activation

An efficient rhodium(III)-catalyzed synthesis of 2H-chromene from N-phenoxyacetamides and cyclopropenes has been developed. The reaction represents the first example of using cyclopropenes as a three-carbon unit in rhodium(III)- catalyzed C(sp2)-H activations.

Facile access to 2,2-diaryl 2: H -chromenes through a palladium-catalyzed cascade reaction of ortho -vinyl bromobenzenes with N -tosylhydrazones

A palladium-catalyzed cascade reaction of ortho-vinyl bromobenzenes with N-tosylhydrazones has been developed, which provides a facile approach to 2,2-disubstituted 2H-chromenes. The migration of palladium from the aryl to vinyl position is crucial, as the in situ produced vinyl palladium intermediate could further react with diazo compounds to generate the reactive species for the sequential annulation. This journal is

Catalysis by β-Cyclodextrin Hydrate - Synthesis of 2,2-Disubstituted 2H-Chromenes in Aqueous Medium

A cost-effective, operationally simple and eco-compatible protocol for the one-pot synthesis of photochromic pyrans by the reaction of propargyl alcohols as well as propargyl ethers with differently substituted phenols under ambient atmosphere in aqueous