4223-17-0 Usage
Description
[(p-octylphenoxy)methyl]oxirane, also known as Octylphenoxypolyethoxyethanol and OPME, is a chemical compound that serves as a surfactant and emulsifier. It is a clear, colorless liquid with a mild odor, soluble in water and some organic solvents, and is widely utilized in various industrial and consumer products.
Uses
Used in Cleaning Products Industry:
[(p-octylphenoxy)methyl]oxirane is used as a surfactant and emulsifier for its ability to reduce surface tension and improve the spreading and absorption of liquids, making it a popular choice in the formulation of cleaning products.
Used in Household Detergents Industry:
OPME is used as a surfactant and emulsifier in household detergents, thanks to its effectiveness in creating oil-in-water emulsions and enhancing the cleaning power of these products.
Used in Personal Care Industry:
In personal care items such as shampoos and liquid soaps, [(p-octylphenoxy)methyl]oxirane is used as a surfactant and emulsifier, contributing to the product's ability to cleanse and emulsify oils and dirt.
Environmental and Health Concerns:
There have been concerns about the potential environmental and health impacts of [(p-octylphenoxy)methyl]oxirane, particularly on aquatic organisms and human health. This has led to increased scrutiny and regulation of its use in some regions.
Check Digit Verification of cas no
The CAS Registry Mumber 4223-17-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,2 and 3 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4223-17:
(6*4)+(5*2)+(4*2)+(3*3)+(2*1)+(1*7)=60
60 % 10 = 0
So 4223-17-0 is a valid CAS Registry Number.
InChI:InChI=1/C17H26O2/c1-2-3-4-5-6-7-8-15-9-11-16(12-10-15)18-13-17-14-19-17/h9-12,17H,2-8,13-14H2,1H3
4223-17-0Relevant articles and documents
Design and synthesis of 1-indol-1-yl-propan-2-ones as inhibitors of human cytosolic phospholipase A2α
Ludwig, Joachim,Bovens, Stefanie,Brauch, Carsten,Elfringhoff, Alwine Schulze,Lehr, Matthias
, p. 2611 - 2620 (2007/10/03)
The synthesis and structure-activity relationship study of a series of 1-indol-1-yl-3-phenoxypropan-2-one inhibitors of cytosolic phospholipase A 2α. (cPLA2α) are described. The compounds were evaluated in a vesicle assay with isolated cPLA2α and in cellular assays with intact human platelets. Systematic variation led to 3-methylhydrogen 1-[3-(4-decyloxyphenoxy)-2-oxopropyl]indole-3,5-dicarboxylate (57), which revealed the highest activity against the isolated enzyme. With an IC50 value of 4.3 nM in this assay, it is one of the most potent in vitro cPLA2α inhibitors known today.
