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42239-75-8

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42239-75-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 42239-75-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,2,3 and 9 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 42239-75:
(7*4)+(6*2)+(5*2)+(4*3)+(3*9)+(2*7)+(1*5)=108
108 % 10 = 8
So 42239-75-8 is a valid CAS Registry Number.

42239-75-8Downstream Products

42239-75-8Relevant articles and documents

Design, synthesis and structure-activity relationship studies of morpholino-1H-phenalene derivatives that antagonize Mcl-1/Bcl-2

Li, Xiangqian,Liang, Xiaomeng,Song, Ting,Su, Pengchen,Zhang, Zhichao

, p. 5738 - 5746 (2015/02/02)

We report herein characteristic studies of Mcl-1 and Bcl-2 dual inhibitors. It was found that a protruding carbonyl group forming hydrogen bond with R263 plays a predominant role compared with the hydrophobic group that occupies the p2 pocket. A series of dual inhibitors representing different parts of the morpholino-1H-phenalene were designed, synthesized and evaluated.

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