42241-07-6

Basic information

• Product Name: 1,2-Benzenediol, 4-amino-5-(2-aminoethyl)-, dihydrochloride
• CAS NO: 42241-07-6
• Molecular Formula: C8H12N2O2.2ClH
• Molecular Weight: 241.117
• Mol File: 42241-07-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenediol, 4-amino-5-(2-aminoethyl)-, dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenediol, 4-amino-5-(2-aminoethyl)-, dihydrochloride(42241-07-6)
• EPA Substance Registry System: 1,2-Benzenediol, 4-amino-5-(2-aminoethyl)-, dihydrochloride(42241-07-6)

Safety Data

• Hazardous Substances Data: 42241-07-6(Hazardous Substances Data)

Upstream product

• 62-31-7 dopamine hydrochloride 

Downstream Products

• 3131-52-0 1H-indole-5,6-diol 
• 145069-19-8 7-amino-8-(2-aminoethyl)-3-hydroxy-2-oxo-2,3,4,10-tetrahydro<3,4-a>iminoethanophenoxazine 

Relevant articles and documents

A New Oxidation Pathway of the Neurotoxin 6-Aminodopamine. Isolation and Characterisation of a Dimer with a Tetrahydroiminoethanophenoxazine Ring System.

Oxidation of the neurotoxin 6-aminodopamine (1) is known to proceed through the o-quinone 3, which undergoes intramolecular cyclisation to give 5,6-dihydroxyindole (6).In a re-examination of the reaction, we have found that at concentrations of 1 higher than 5 * 10-3 M a quite different course prevails, leading to the formation of the novel 7-amino-8-(2-aminoethyl)-3-hydroxy-2-oxo-2,3,4,10-tetrahydroiminoethanophenoxazine (7).Product 7 was formed by aerobic, chemical (persulphate, periodate) or enzymatic (tyrosinase, peroxidase/H2O2) oxidation of 1.On acetylation, 7 afforded the tetraacetate 8.Oxidation of the model compound 5-amino-4-methylcatechol (9) proceeded similarly as that of 1, to give the tetrahydrophenoxazinedione 11.