42290-98-2

Basic information

• Product Name: Benzenemethanamine, a-methyl-N-(2-methylpropyl)-
• CAS NO: 42290-98-2
• Molecular Formula: C12H19N
• Molecular Weight: 177.29
• Mol File: 42290-98-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, a-methyl-N-(2-methylpropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, a-methyl-N-(2-methylpropyl)-(42290-98-2)
• EPA Substance Registry System: Benzenemethanamine, a-methyl-N-(2-methylpropyl)-(42290-98-2)

Safety Data

• Hazardous Substances Data: 42290-98-2(Hazardous Substances Data)

Upstream product

• 613-91-2 acetophenone oxime 
• 78-84-2 isobutyraldehyde 
• 78-81-9 isobutylamine 
• 98-86-2 acetophenone 
• 72924-95-9 N-(α-methylbenzyl)isobutyramide 
• 19340-97-7 N-isobutyl-1-phenylethan-1-imine 

Downstream Products

• 133469-20-2 (R)-N-isobutyl-1-phenylethylamine 

Relevant articles and documents

Hydroamination of carbonyl compounds with oximes

N-alkyl(cycloalkyl)benzylamines, p-fluorobenzylamines, (1-phenylethyl) amines, [1-(p-fluorophenyl)ethyl]amines were synthesized by hydroamination of aldehydes and ketones with oximes.

Iron-catalyzed transfer hydrogenation of imines assisted by an iron-based Lewis acid

An iron-catalyzed transfer hydrogenation of N-aryl and N-alkyl imines using isopropanol as the hydrogen donor is reported for the first time. A combination of two iron complexes serving different roles is the key for the success of this catalytic system. As a result, an environmentally friendly and precious metal-free transfer hydrogenation of imines has been developed. The use of a suitable co-catalyst as an activator not only led to efficient transfer hydrogenation, but also showed potential in enantioselective transformation.

A highly enantioselective organocatalytic method for reduction of aromatic N-alkyl ketimines

A study has demonstrated the development of a highly enantioselective catalytic method for the reduction of aromatic N-alkyl ketimines by trichlorosilane under mild conditions using the newly designed Lewis base organocatalyst that incorporates C- and S-chirality. The S-chiral sulfinamide group in these catalysts plays a crucial role similar to the carboxamide groups as Lewis base for the activation of HSiCl3, and also serves as a source of chirality that the carboxamide group lacks for the asymmetric induction. The results of the study showed that excellent enantioselectivities of up to 99.6% ee and high yields were obtained for a wide range of substrates. Further works is also in progress to clarify the mechanism of the transformation and explore the full application scope of the present catalyst system.