42313-49-5

Basic information

• Product Name: methyl 3-(3-methoxyanilino)propionate
• Synonyms: methyl 3-(3-methoxyanilino)propionate
• CAS NO: 42313-49-5
• Molecular Weight: 209.245
• Mol File: 42313-49-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: methyl 3-(3-methoxyanilino)propionate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(3-methoxyanilino)propionate(42313-49-5)
• EPA Substance Registry System: methyl 3-(3-methoxyanilino)propionate(42313-49-5)

Safety Data

• Hazardous Substances Data: 42313-49-5(Hazardous Substances Data)

Upstream product

• 536-90-3 m-Anisidine 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 1422186-10-4 methyl N-tosyl-3-(3-methoxyanilino)propionate 
• 1422186-26-2 1-tosyl-4,4-dimethyl-7-methoxy-1,2,3,4-tetrahydroquinoline 
• 1422186-27-3 1-tosyl-4,4-dimethyl-5-methoxy-1,2,3,4-tetrahydroquinoline 
• 58750-87-1 N-tosyl-m-anisidine 
• 1422186-16-0 N-tosyl-4-(3-methoxyanilino)-2-methyl-2-butanol 
• 21988-35-2 1-Benzolsulfonyl-4-oxo-7-methoxy-1,2,3,4-tetrahydro-chinolin 
• 95034-95-0 2-methoxycarbonyl-1-(m-methoxyphenyl)-3-pyrrolidinone 
• 914929-37-6 4-methoxycarbonyl-1-(m-methoxyphenyl)-3-pyrrolidone 
• 95034-94-9 methyl 3-propanoate 
• 18042-74-5 3-[(5-Chloro-2-diacetylamino-benzyl)-(3-methoxy-phenyl)-amino]-propionic acid methyl ester 
• 18009-63-7 3-[(2-Chloro-6-diacetylamino-benzyl)-(3-methoxy-phenyl)-amino]-propionic acid methyl ester 
• 15908-77-7 N-benzenesulfonyl-N-(3-methoxy-phenyl)-β-alanine 
• 1246521-41-4 C₂₀H₂₂N₄O₄ 
• 1246521-42-5 C₁₉H₂₀N₄O₄ 

Relevant articles and documents

Fast, easy, solvent-free, microwave-promoted Michael addition of anilines to α,β-unsaturated alkenes: synthesis of N-aryl functionalized β-amino esters and acids

The rapid, simple, microwave-promoted synthesis of N-aryl functionalized β-amino esters using Michael addition reactions is presented. Reactions are performed neat at 200 °C for 20 min and are catalyzed by acetic acid. The esters can be easily hydrolyzed to the corresponding N-aryl functionalized β-amino acids.

Boric acid/glycerol as an efficient catalyst for synthesis of thiomorpholine 1,1-dioxide by double michael addition reaction in water

Thiomorpholine 1,1-dioxides were prepared with double Michael addition reaction of aromatic amines to divinyl sulfone catalyzed by boric acid/glycerol in water. This catalyst system was also used for the Michael addition reaction of aromatic amines to electron-deficient alkenes. The reaction is simple and green and gives good to excellent yields.

Assessment and use of two silicon carbide multi-well plates for library synthesis and proteolytic digests using microwave heating

The use of two silicon carbide plates is reported for the preparation of three libraries of organic molecules using microwave heating. In addition, a preliminary study has been carried out, showing that one of the plates can also be used in a proteomics setting. Both the 24-position and 48-position plates heated evenly when irradiated with microwave energy. The 48-position plate was used to prepare a library of N-aryl functionalized β-amino esters via an aza-Michael reaction between anilines and Michael acceptors. The 24-position plate was used to prepare a library of biaryls via a Suzuki coupling methodology and a library of 1,4-dihydropyridines via a Hantzsch synthesis. The 48-position plate was also used to perform the proteolytic digestion of insulin chain B by trypsin. The Royal Society of Chemistry 2009.