42329-17-9

Basic information

• Product Name: Hexahydro-oxazolo[3,4-a]pyridin-3-one
• Synonyms: Hexahydro-oxazolo[3,4-a]pyridin-3-one
• CAS NO: 42329-17-9
• Molecular Formula: C₇H₁₁NO₂
• Molecular Weight: 141.16774
• Mol File: 42329-17-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 11-13 °C
• Boiling Point: 96 °C(Press: 0.08 Torr)
• Appearance: /
• Density: 1.19±0.1 g/cm3(Predicted)
• PKA: -1.34±0.20(Predicted)
• CAS DataBase Reference: Hexahydro-oxazolo[3,4-a]pyridin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: Hexahydro-oxazolo[3,4-a]pyridin-3-one(42329-17-9)
• EPA Substance Registry System: Hexahydro-oxazolo[3,4-a]pyridin-3-one(42329-17-9)

Safety Data

• Hazardous Substances Data: 42329-17-9(Hazardous Substances Data)

Upstream product

• 5707-04-0 Phenylselenyl chloride 
• 86990-51-4 N-benzyloxycarbonyl-5-hexenylamine 
• 112476-25-2 N-Ethoxycarbonylhex-5-enylamine 
• 87842-81-7 (8aSR)-1,7,8,8a-tetrahydrooxazolo[3,4-a]pyridin-3-one 

Relevant articles and documents

Diastereoselective functionalizations of enecarbamates derived from pipecolic acid towards 5-guanidinopipecolates as arginine mimetics

Various substituents could be diastereoselectively introduced into the 5-position of pipecolic acid via electrophilic or free-radical-initiated addition to the carbon-carbon double bond of endocyclic enecarbamates derived from pipecolic acid. This study a

The Cyclization of Hex-5-enylcarbamates and Related Compounds with Benzeneselenyl chloride and Some Reactions of the 2-Substituted Piperidine Products

The reaction of hex-5-enylcarbamates with benzeneselenyl chloride gives adducts which cyclize in the presence of silica or stannic chloride, to 2-phenylselenomethylpiperidine derivatives which are unstable, both thermally and on silica.The selenoxides also undergo a Pummerer-type reaction to form 2-acetoxy(phenylseleno)methylpiperidine systems which can be oxidatively converted into a piperidine 2-aldehyde.The selenoxides react with carbon tetrachloride in base to form a 2,2,2-trichloroethyl substituent.Both the selenoxides and the phenylseleno groups of the cyclized products can be displaced by nucleophiles.Ethy hept-6-enylcarbamate did not give a cyclic product with benzeneselenyl chloride and silica, and gave a poor yield of a hexahydroazepine with stannic chloride.Hex-5-enamide cyclized to give a lactone, rather than a lactam, product.Hex-5-enenitrile gave Ritter reaction products with benzeneselenyl chloride in acetonitrile, and a dimer in non-nucleophilic solvents.