42473-85-8Relevant articles and documents
Regioselective gold-catalyzed oxidative C-N bond formation
Marchetti, Louis,Kantak, Abhishek,Davis, Riley,Deboef, Brenton
, p. 358 - 361 (2015)
A novel protocol for the regioselective intermolecular amination of various arenes has been developed. By using an I(III) oxidant in the presence of a Au(I) catalyst, a direct and novel route for regioselectively accessing a variety of substituted aniline moieties has been achieved with yields as high as 90%. Mechanistic insight suggests that regioselectivity can be predicted based on electrophilic aromatic metalation patterns.