42521-08-4

Basic information

• Product Name: 2,6-DICHLOROPYRIDINE-4-CARBONYL CHLORIDE
• Synonyms: 2,6-DICHLORO-ISONICOTINOYL CHLORIDE;2,6-DICHLOROPYRIDINE-4-CARBONYL CHLORIDE;BUTTPARK 43\57-15;2,6-Dichloropyridine-4-carboxylic chloride;4-(Chlorocarbonyl)-2,6-dichloropyridine, 4-(Chloroformyl)-2,6-dichloropyridine
• CAS NO: 42521-08-4
• Molecular Formula: C₆H₂Cl₃NO
• Molecular Weight: 210.45
• Product Categories: Carbonyl Chlorides;Pyridines;Carbonyl Chlorides;Building Blocks;C5 to C6;C6 to C7;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks
• Mol File: 42521-08-4.mol
• Article Data: 11

Chemical Properties

• Melting Point: 23-25°C
• Boiling Point: 140 °C
• Flash Point: 110℃
• Appearance: /
• Density: 1.537
• Vapor Pressure: 0.0038mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2,6-DICHLOROPYRIDINE-4-CARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DICHLOROPYRIDINE-4-CARBONYL CHLORIDE(42521-08-4)
• EPA Substance Registry System: 2,6-DICHLOROPYRIDINE-4-CARBONYL CHLORIDE(42521-08-4)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: 3261
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 42521-08-4(Hazardous Substances Data)

Usage

General Description

2,6-Dichloropyridine-4-carbonyl chloride, also known as 2,6-dichloro-4-pyridinecarbonyl chloride, is a chemical compound with molecular formula C6H2Cl3NO and a molecular weight of 204.45 g/mol. It is a highly reactive and toxic compound commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is a colorless to light yellow liquid with a pungent odor and is flammable. It is primarily used in the production of insecticides, herbicides, and fungicides. 2,6-Dichloropyridine-4-carbonyl chloride is known to be highly corrosive and irritant to skin, eyes, and respiratory system, and should be handled with extreme caution in a well-ventilated area with appropriate personal protective equipment.

InChI:InChI=1/C6H2Cl3NO/c7-4-1-3(6(9)11)2-5(8)10-4/h1-2H

Upstream product

• 5398-44-7 2,6-dichloropyridine-4-carboxylic acid 
• 10026-13-8 phosphorus pentachloride 
• 99-11-6 citrazinic acid 
• 10025-87-3 trichlorophosphate 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 1604-14-4 2,6-dichloroisonicotinic acid ethyl ester 
• 113293-70-2 2,6-dichloropyridine-4-carbaldehyde 
• 57803-45-9 N-(2,6-Dichlor-isonicotinoyl)-oxazolidin 
• 57803-44-8 (2,6-dichloropyridin-4-yl)(morpholino)methanone 
• 82140-55-4 (E)-2-(2,6-Dichloro-pyridine-4-carbonyl)-3-methylamino-but-2-enoic acid methyl ester 
• 2402-78-0 2,6-dichloropyridine 
• 89281-13-0 2,6-dichloropyridine-4-carboxamide 
• 42521-09-5 methyl 2,6-dichloroisonicotinate 
• 2587-02-2 2,6-dichloro-[4]pyridylamine 
• 1000201-31-9 2-(2,6-dichloroisonicotinoyl)benzonitrile 
• 5398-44-7 2,6-dichloropyridine-4-carboxylic acid 
• 32710-65-9 2,6-dichloro-4-cyanopyridine 
• 88579-63-9 (2,6-dichloropyridin-4-yl)methanamine 
• 101990-69-6 (2,6-dichloropyridin-4-yl)methanol 

Relevant articles and documents

Synthesis of novel pyridine and pyrimidine derivatives as potential inhibitors of HIV-1 reverse transcriptase using palladium-catalysed C-N cross-coupling and nucleophilic aromatic substitution reactions

Palladium-mediated cross-coupling reactions are used in the successful construction of a small library of flexible heteroatom-linked diarylpyridine target compounds, including pyridines bearing a secondary amide substituent. Heteroatom-linked diarylpyrimidine derivatives bearing a chlorine substituent are prepared by base-catalysed nucleophilic aromatic substitution reactions without the need for palladium catalysis.

Nitrogenous heterocyclic compound with nematocidal activity, preparation method and application thereof

The invention relates to a nitrogenous heterocyclic compound with nematocidal activity, a preparation method and application thereof. Specifically, the invention discloses a compound with a formula (I) or an optical isomer, cis-trans isomer or acceptable salt in agricultural pharmacology and a preparation method thereof. The invention further discloses an agricultural composition containing the compound and application thereof. The compound has excellent nematocidal activity.

Titanocene(III)-catalyzed conversion of N-(epoxyalkyl)anilines into indolines

Densely substituted indolines and azaindolines can be obtained by the titanocene(III) chloride catalyzed reductive opening of N-(oxiran-2-ylmethyl) anilines. The reaction optimization, substrate scope, and limitations are discussed, and a mechanistic pathway for the epoxideopening rearrangement is proposed. ARKAT-USA, Inc.