42524-21-0

Basic information

• Product Name: Ethanone, 1-(5-bromo-2-hydroxyphenyl)-, oxime
• CAS NO: 42524-21-0
• Molecular Formula: C8H8BrNO2
• Molecular Weight: 230.061
• Mol File: 42524-21-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(5-bromo-2-hydroxyphenyl)-, oxime(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(5-bromo-2-hydroxyphenyl)-, oxime(42524-21-0)
• EPA Substance Registry System: Ethanone, 1-(5-bromo-2-hydroxyphenyl)-, oxime(42524-21-0)

Safety Data

• Hazardous Substances Data: 42524-21-0(Hazardous Substances Data)

Upstream product

• 1450-75-5 5-Bromo-2-hydroxyacetophenone 

Downstream Products

• 1450-75-5 5-Bromo-2-hydroxyacetophenone 
• 66033-76-9 5-bromo-3-methyl-1,2-benzisoxazole 

Relevant articles and documents

ISOXAZOLINE DERIVATIVES AND THEIR USES IN AGRICULTURE RELATED APPLICATION

The present invention provides isoxazoline derivatives and uses thereof in agriculture; in particular, the present invention provides a compound having formula (I), or a stereoisomer, an N-oxide or a salt thereof, preparation methods thereof, and compositions containing these compounds and uses thereof in agriculture, particularly uses as herbicide active ingredients for controlling unwanted plants; wherein R1, R2, R3, R4, n, R5, R6 and Hy are as described in the invention.

Acid Catalyzed Direct-Amidation-Dehydrocyclization of 2-Hydroxy-acetophenones to Benzoxazoles by a One-Pot Sustainable Synthesis

A series of 2-methyl-benzoxazoles have been synthesized starting from 2-hydroxy-acetophenones via a one-pot three steps reaction. Hydroxylamonium salt has been used as amidation agent. The reaction occurs with different anions, but the best results is achieved with hydroxylamonium hydrchloride. Despite the number of consecutive stages, the reaction is highly selective. Mild reaction conditions and various solvents can be used, but trifluoroacetic acid is the preferred. Almost, complete recovery of the trifluoroacetic acid can be achieved by vacuum distillation. The role of trifluoroacetic acid, as well as, of the hydroxylamonium salt suggests a cooperative effect leading to high selective formation of 2-methyl-benzoxazoles. Graphical Abstract: One-pot TFA catalyzed synthesis of benzoxazoles starting from 2-hydroxyacetophenones. (Chemical Equation Presented).

Synthesis of 1,2-benzisoxazole 2-oxides

(Chemical Equation Presented) A series of 2-hydroxyaryl ketoximes were converted to the corresponding 1,2- benzisoxazole 2-oxides by treatment with iodobenzene diacetate (in acetic acid or methanol) or N-chlorosuccinimide in water. Both methods gave moderate to excellent yields for a variety of substituted oximes under mild conditions within short reaction times. The latter method has the advantages of an aqueous solvent and lack of halogenated organic by-products. Copyright Taylor & Francis Group, LLC.