425427-88-9 Usage
Description
6-CHLORO-3-INDOXYL-ALPHA-D-MANNOPYRANOSIDE is a synthetic compound that serves as a chromogenic substrate for the enzyme α-mannosidase. It is characterized by its ability to produce a salmon-colored precipitate upon enzymatic cleavage, which makes it a useful tool in various applications.
Uses
Used in Diagnostic Applications:
6-CHLORO-3-INDOXYL-ALPHA-D-MANNOPYRANOSIDE is used as a diagnostic agent for the detection and monitoring of α-mannosidase activity. The enzyme plays a crucial role in the metabolism of complex carbohydrates, and its abnormal activity can be indicative of certain health conditions. The salmon-colored precipitate produced upon cleavage allows for easy visualization and assessment of the enzyme's activity.
Used in Research and Development:
In the field of research and development, 6-CHLORO-3-INDOXYL-ALPHA-D-MANNOPYRANOSIDE is used as a research tool for studying the function and regulation of α-mannosidase. Its chromogenic properties make it an ideal candidate for investigating the enzyme's role in various biological processes and its potential as a therapeutic target for certain diseases.
Used in Pharmaceutical Industry:
6-CHLORO-3-INDOXYL-ALPHA-D-MANNOPYRANOSIDE is used as a starting material or intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable building block for the development of new drugs targeting α-mannosidase-related conditions.
Used in Quality Control:
In the quality control of pharmaceutical products, 6-CHLORO-3-INDOXYL-ALPHA-D-MANNOPYRANOSIDE can be used as a reference standard or control substance to ensure the accuracy and reliability of α-mannosidase activity assays. This helps in maintaining the quality and consistency of diagnostic tests and therapeutic products that rely on the measurement or modulation of α-mannosidase activity.
Check Digit Verification of cas no
The CAS Registry Mumber 425427-88-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,5,4,2 and 7 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 425427-88:
(8*4)+(7*2)+(6*5)+(5*4)+(4*2)+(3*7)+(2*8)+(1*8)=149
149 % 10 = 9
So 425427-88-9 is a valid CAS Registry Number.
425427-88-9Relevant articles and documents
Substrate and preparation method and application thereof
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Paragraph 0022; 0026, (2019/05/15)
The invention discloses a substrate namely alpha-D-glucoside for detecting activity of alpha-glucosidases, and further discloses a synthesis technology of the substrate. The synthesis technology comprises the steps of enabling a compound alpha-D-glucose and acetyl chloride to be subjected to a reaction, and performing purification to obtain alpha-D- pentacetylglucose; catalyzing the obtained substances with N,N-Dimethyl-1,3-diaminopropane, performing pickling, performing extraction, performing drying, and performing purifying to obtain 2,3,4,6-tetra-O-acetyl-alpha-D-acetyl-glucosamine; catalyzing the obtained substances in a dichloromethane solution, performing a reaction with trichloroacetonitrile, performing filtering, and performing purifying to obtain 2,3,4,6-tetra-O-acetyl-beta-D-glucosyl trichloroacetimidate; performing catalyzing on the obtained substances in a dichloromethane solution, performing a reaction with chromogen or fluorophore, performing extraction, merging organic phases, performing drying, performing concentrating, performing methanol redissolution, performing crystal nourishing at 4 DEG C, and performing filtering to obtain 2,3,4,6-tetra-O-acetyl-alpha-D-glucoside; and catalyzing the obtained substances in a methanolic solution, performing a reaction, then performing decoloring adsorption, performing filtering, and performing purifying. The synthesis technology of the substrate is simple and high in yield, the sensitivity of a reagent kit can be improved, the stability is good, and the specificity is high.
