425671-29-0

Basic information

• Product Name: 2-Methyl-2-[4-[3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl]phenoxy]propionic acid
• Synonyms: LY-674; LY-518674; 2-methyl-2-(4-{3-[1-(4-methylbenzyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazol-3-yl]propyl}phenoxy)propanoic acid
• CAS NO: 425671-29-0
• Molecular Formula: C₂₃H₂₇N₃O₄
• Molecular Weight: 409.4782
• Mol File: 425671-29-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 575.852°C at 760 mmHg
• Flash Point: 302.065°C
• Density: 1.21g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.594
• CAS DataBase Reference: 2-Methyl-2-[4-[3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl]phenoxy]propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-2-[4-[3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl]phenoxy]propionic acid(425671-29-0)
• EPA Substance Registry System: 2-Methyl-2-[4-[3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl]phenoxy]propionic acid(425671-29-0)

Safety Data

• Hazardous Substances Data: 425671-29-0(Hazardous Substances Data)

Usage

General Description

2-Methyl-2-[4-[3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl]phenoxy]propionic acid is a complex chemical compound that belongs to the class of propionic acid derivatives. It contains a 1,2,4-triazole ring and a benzyl group, and is also known as DPX-KN128. 2-Methyl-2-[4-[3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl]phenoxy]propionic acid is not naturally occurring and is likely to be synthetically derived. It may have potential applications in the field of pharmaceutical research and drug development due to its unique structure and properties. Further studies and research are needed to determine its specific uses and potential benefits.

Upstream product

• 425674-22-2 2-methyl-2-(4-{3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]propyl}phenoxy)propionic acid methyl ester 
• 958873-55-7 5-[3-(4-hydroxyphenyl)propyl]-2-(4-methylbenzyl)-2,4-dihydro-[1,2,4]triazol-3-one 
• 67-66-3 chloroform 
• 67-64-1 acetone 
• 958873-54-6 5-[3-[4-(2-hydroxy-1,1-dimethylethoxy)phenyl]propyl]-2-(4-methylbenzyl)-2,4-dihydro[1,2,4]triazol-3-one 
• 20637-08-5 4-(4-methoxyphenyl)butyric acid methyl ester 
• 22320-10-1 methyl 4-(4-hydroxyphenyl)butanoate 
• 425672-61-3 4-[4-(1-tert-butoxycarbonyl-1-methyl-ethoxy)phenyl]butyric acid methyl ester 
• 425672-62-4 2-[4-(3-hydrazinocarbonylpropyl)phenoxy]-2-methylpropionic acid tert-butyl ester 
• 425672-76-0 2-(4-{3-[4-(2,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]propyl}phenoxy)-2-methylpropionic acid methyl ester 
• 425669-64-3 2-(4-{3-[4-(2,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]propyl}phenoxy)-2-methylpropionic acid 
• 425672-69-1 2-(4-{4-[N'-(2,4-dimethoxybenzylaminocarbonyl)hydrazino]-4-oxo-butyl}phenoxy)-2-methylpropionic acid tert-butyl ester 
• 425674-21-1 2-(4-{3-[4-(2,4-dimethoxybenzyl)-1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]propyl}phenoxy)-2-methylpropionic acid methyl ester 
• 425675-46-3 2-[4-[3-[4,5-dihydro-1-[(4-methylphenyl)methyl]-5-oxo-1H-1,2,4-triazol-3-yl]propyl]phenoxy]-2-methylpropanoic acid ethyl ester 

Downstream Products

• 958873-54-6 5-[3-[4-(2-hydroxy-1,1-dimethylethoxy)phenyl]propyl]-2-(4-methylbenzyl)-2,4-dihydro[1,2,4]triazol-3-one 
• 958873-47-7 2-(2-bromo-4-[3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]propyl]phenoxy)-2-methyl propionic acid 

Relevant articles and documents

The role of new technologies in defining a manufacturing process for ppara agonist ly518674

The impact of several new technologies on the development of a manufacturing process for LY518674 is described. Extensive use of process analytical technology (PAT) throughout development, both at laboratory and pilot-plant scale, enabled data-rich experi

The synthesis of three isotopomers of 2-methyl-2-(4-[3-[1-(4-methylbenzyl)- 5-oxo-4,5-dihydro-1H-[1,2,4]triazol-3-yl]propyl]phenoxy)propionic acid, a potent and selective peroxisome proliferator-activated receptor alpha agonist

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