4257-87-8

Basic information

• Product Name: 2,2,2-Trichloro-N-(2-methylphenyl)acetamide
• Synonyms: 2,2,2-Trichloro-N-(2-methylphenyl)acetamide;AcetaMide, 2,2,2-trichloro-N-(2-Methylphenyl)-
• CAS NO: 4257-87-8
• Molecular Formula: C₉H₈Cl₃NO
• Molecular Weight: 252.52
• Mol File: 4257-87-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2,2-Trichloro-N-(2-methylphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-Trichloro-N-(2-methylphenyl)acetamide(4257-87-8)
• EPA Substance Registry System: 2,2,2-Trichloro-N-(2-methylphenyl)acetamide(4257-87-8)

Safety Data

• Hazardous Substances Data: 4257-87-8(Hazardous Substances Data)

Usage

General Description

2,2,2-Trichloro-N-(2-methylphenyl)acetamide is a chemical compound used as a herbicide. It is a white crystalline solid with a strong chemical odor. 2,2,2-Trichloro-N-(2-methylphenyl)acetamide is effective in controlling the growth of various types of weeds and unwanted plants in agricultural and industrial applications. It works by inhibiting the enzyme acetolactate synthase, which is essential for the synthesis of branched-chain amino acids in plants. However, this compound should be handled with caution as it is toxic to aquatic organisms and may cause skin and eye irritation in humans. It is important to follow safety guidelines and regulations when using 2,2,2-Trichloro-N-(2-methylphenyl)acetamide.

Upstream product

• 95-53-4 o-toluidine 
• 76-02-8 trifluoroacetyl chloride 
• 116-16-5 1,1,1,3,3,3-hexachloro-propan-2-one 
• 76-03-9 trichloroacetic acid 
• 515-84-4 Ethyl trichloroacetate 

Downstream Products

• 7477-94-3 2-methyl-4,6-dinitroaniline 
• 113260-70-1 N-(o-tolylcarbamoyl)benzamide 
• 1081272-48-1 N-(2-methylphenyl)-N'-(6-methylbenzothiazol-2-yl)urea 
• 1018186-39-4 N-(2-methylphenyl)-N'-(6-chlorobenzothiazol-2-yl)urea 
• 1430847-70-3 14-O-{1-[(2-methylphenyl)ureido]-2-methylpropan-2-ylthioacetyl}mutilin 

Relevant articles and documents

Synthesis and antibacterial activities of pleuromutilin derivatives containing aryl urea groups

A series of novel pleuromutilin derivatives containing aryl urea groups was synthesized and their antibacterial activities were evaluated in vitro against S. aureus ATCC 26113, S.aureus SC, S. albus ATCC 8799 and P. aeruginosa ATCC 27853. Most of compound

Formation of N-Substituted Trichloroacetamides from Amines and Hexachloroacetone

Procedures are described for converting primary amines into their well-crystalline trichloroacetyl-derivatives by treatment with hexachloroacetone under mild conditions.Although secondary aromatic N-methylamines are unaffected by hexachloroacetone, saturated heterocyclic amines react vigorously.A mechanistic study using 2-amino-4-t-butylthiazole showed that the reaction is first order in hexachloroacetone, second order in amine, and base-catalysed; there is no appreciable kinetic isotope (H/D) effect nor accumulation of intermediates during the reaction.A sequence which accommodates these results is suggested.