42613-29-6

Basic information

• Product Name: CYTOHELICASE
• Synonyms: CYTOHELICASE;cytohelicase from helix pomatia;Helicase;Helicase (Helix pomatia);Snail helicase
• CAS NO: 42613-29-6
• Molecular Formula: C14H23N
• Molecular Weight: 205.34
• EINECS: 255-913-9
• Product Categories: Carbohydrate Hydrolysis;Application Index;Carbohydrate and PTM AnalysisApplication Index;Carbohydrate hydrolysis&PTM analysis
• Mol File: 42613-29-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: CYTOHELICASE(CAS DataBase Reference)
• NIST Chemistry Reference: CYTOHELICASE(42613-29-6)
• EPA Substance Registry System: CYTOHELICASE(42613-29-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 42613-29-6(Hazardous Substances Data)

Usage

Description

CYTOHELICASE is an enzyme that plays a crucial role in the process of DNA repair and recombination. It is involved in the unwinding of DNA helix, which is essential for various cellular processes such as replication, transcription, and DNA repair. The enzyme is known for its ability to cleave and religate double-stranded DNA, making it a valuable tool in molecular biology research.

Uses

Used in Molecular Biology Research:
CYTOHELICASE is used as a tool for DNA manipulation in molecular biology research. It is particularly useful for studying the effects of gene disruptions on protein secretion in various yeast cultures, such as Kluyveromyces lactis and Saccharomyces cerevisiae.
Used in Cytohelicase Assay:
The enzyme from Sigma has been specifically utilized for cytohelicase assay, which helps in understanding the role of CYTOHELICASE in DNA repair and recombination processes. This assay is essential for evaluating the functionality and activity of the enzyme in different experimental setups.

Biochem/physiol Actions

Cytohelicase from Helix pomatia is used in the preparation of synaptonemal complex spreading techniques along with bovine serum albumin. It plays an important role in the digestion of cell wall. Cytohelicase interacts with chromatin and improves the adhesion of synaptonemal complexes to the hydrophobic plastic film.