426265-73-8

Basic information

• Product Name: 4-Bromo-2-chlorobenzamide
• Synonyms: 4-Bromo-2-chlorobenzamide
• CAS NO: 426265-73-8
• Molecular Formula: C₇H₅BrClNO
• Molecular Weight: 234.48
• Mol File: 426265-73-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Bromo-2-chlorobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-2-chlorobenzamide(426265-73-8)
• EPA Substance Registry System: 4-Bromo-2-chlorobenzamide(426265-73-8)

Safety Data

• Hazardous Substances Data: 426265-73-8(Hazardous Substances Data)

Usage

Description

4-Bromo-2-chlorobenzamide is a chemical compound with the molecular formula C7H5BrClNO. It is a white solid that is insoluble in water but soluble in organic solvents. 4-Bromo-2-chlorobenzamide is known for its unique properties and reactivity, making it a valuable component in various applications across different industries.

Uses

Used in Pharmaceutical Industry:
4-Bromo-2-chlorobenzamide is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure and reactivity contribute to the development of new drugs and medications, enhancing the range of treatments available for various medical conditions.
Used in Agricultural Chemicals:
In the agricultural sector, 4-Bromo-2-chlorobenzamide serves as an intermediate in the production of agricultural chemicals. Its role in creating effective pesticides and other agrochemicals helps improve crop protection and yield.
Used in Organic Chemistry Research:
4-Bromo-2-chlorobenzamide is utilized as a reagent in organic chemistry reactions. Its distinctive properties make it a useful tool for researchers in the field, facilitating the exploration of new chemical reactions and the synthesis of novel compounds.
Overall, 4-Bromo-2-chlorobenzamide's potential applications in medicine, agriculture, and chemical research highlight its importance as a versatile chemical compound with wide-ranging utility.

Upstream product

• 154607-01-9 4-bromo-2-chlorobenzonitrile 
• 79-37-8 oxalyl dichloride 
• 59748-90-2 4-Bromo-2-chloro-benzoic Acid 
• 698-67-9 p-bromobenzamide 

Downstream Products

• 1218791-12-8 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide 
• 1459732-37-6 2-chloro-4-(3-((2-oxo-1,2-dihydroquinolin-6-yl)methyl)-3H-[1,2,3]triazolo[4,5-b]pyridin-5-yl)benzamide 
• 1350428-31-7 2-chloro-4-(3-(quinolin-6-ylmethyl)-3H-imidazo[4,5-b]pyridin-5-yl)benzamide 
• 1459732-41-2 2-chloro-4-(3-(quinolin-6-ylmethyl)-3H-imidazo[4,5-b]pyridin-5-yl)benzamide hydrochloride 
• 1459732-49-0 2-chloro-4-(3-(quinolin-6-ylmethyl)-3H-imidazo[4,5-b]pyridin-5-yl)benzamide 2,2,2-trifluoroacetate 

Relevant articles and documents

Acid-promoted palladium(II)-catalyzed ortho-halogenation of primary benzamides: En route to halo-arenes

Br?nsted acid-promoted palladium(II)-catalyzed regioselective installation of halogens (Br, Cl, and I) to the aromatic ring of benzamide derivatives has been achieved using primary amides. A wide variety of benzamides were compatible under established conditions to afford the halogenated products without installing any external auxiliary. Mild reaction conditions, use of primary amide as a directing group, external additive-free conditions, and gram-scale reaction are some appealing features of this protocol. Detailed experimental results revealed that Br?nsted acid plays a critical role in this transformation.

SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS

Compounds of Formula I: and salts thereof in which R1, R2, R2a, R3, n, X and ring B have the meanings given in the specification, are inhibitors of mTOR and are useful in the treatment of diseases which are sensitive to inhibition of mTOR, such as cancers.