426463-20-9 Usage
General Description
2-BROMO-5-IODO-3-NITROPYRIDINE is a chemical compound with the molecular formula C5H3BrIN2O2. It is a yellow crystalline solid with a molecular weight of 305.89 g/mol. 2-BROMO-5-IODO-3-NITROPYRIDINE is used in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in organic chemistry and can be used in the production of various functional materials. 2-BROMO-5-IODO-3-NITROPYRIDINE is considered to be a hazardous substance and should be handled with care, as it may cause irritation to the skin, eyes, and respiratory system.
Check Digit Verification of cas no
The CAS Registry Mumber 426463-20-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,6,4,6 and 3 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 426463-20:
(8*4)+(7*2)+(6*6)+(5*4)+(4*6)+(3*3)+(2*2)+(1*0)=139
139 % 10 = 9
So 426463-20-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H2BrIN2O2/c6-5-4(9(10)11)1-3(7)2-8-5/h1-2H
426463-20-9Relevant articles and documents
Synthetic method of 2-bromo-5-iodopyridin-3-amine
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, (2017/11/29)
The invention relates to a synthetic method of 2-bromo-5-iodopyridin-3-amine. According to the synthetic method, the technical problem that an effective synthetic method of 2-bromo-5-iodopyridin-3-amine is lacked is mainly solved. The synthetic method comprises the following steps: generating a compound 1 by virtue of 2-amino-3-nitropyridine, sodium periodate and iodine in mixed liquid of water and acetic acid under the catalysis of concentrated sulfuric acid; reacting by virtue of the compound 1, hydrobromic acid, sodium nitrite and cuprous bromide under a diazotization reaction condition, so as to generate a compound 2; and reacting by virtue of the compound 2, ammonium chloride and iron powder in mixed liquid of ethanol and water, so as to reduce nitro into amino and generate a target compound 3, wherein the reaction formula is shown in the description. As an expensive medical intermediate, 2-bromo-5-iodopyridin-3-amine is widely applied in the pharmaceutical industry.
