426841-80-7

Basic information

• Product Name: (1R,2S)-cis-2-phenyl-1,2-dihydronaphthalen-1-ol
• Synonyms: (1R,2S)-cis-2-phenyl-1,2-dihydronaphthalen-1-ol
• CAS NO: 426841-80-7
• Molecular Weight: 222.287
• Mol File: 426841-80-7.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (1R,2S)-cis-2-phenyl-1,2-dihydronaphthalen-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-cis-2-phenyl-1,2-dihydronaphthalen-1-ol(426841-80-7)
• EPA Substance Registry System: (1R,2S)-cis-2-phenyl-1,2-dihydronaphthalen-1-ol(426841-80-7)

Safety Data

• Hazardous Substances Data: 426841-80-7(Hazardous Substances Data)

Upstream product

• 573-57-9 1,4-dihydronaphthalene-1,4-epoxide 
• 2996-92-1 phenyl trimethylsiloxane 
• 98-80-6 phenylboronic acid 
• 4406-72-8 2-phenyl[1,3,2]dioxaborolane 
• 573-57-9 1,4-epoxy-1,4-dihydronaphthalene 
• 5123-13-7 5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane 

Downstream Products

• 426841-92-1 (1R,2S)-2-phenyl-1,2,3,4,-tetrahydronaphthalen-1-ol 

Relevant articles and documents

Rhodium-Catalyzed Asymmetric Ring Opening of Oxabicyclic Alkenes with Organoboronic Acids

(Equation Presented) The first rhodium(I)-catalyzed asymmetric addition of organoboronic acids to oxabicyclic alkenes is reported. This asymmetric ring-opening (ARO) reaction can proceed in high yield under very mild conditions with electronically diverse

Water-Promoted Palladium-Catalyzed Asymmetric Ring-Opening of Oxabenzonorbornadienes with Alkoxysilanes

Water-promoted palladium-catalyzed asymmetric ring-opening (ARO) reaction of oxabenzonorbornadienes with a wide variety of alkoxysilanes has been developed in a one-pot fashion, yielding cis-1,2-dihydronaphthalen-1-ols in favourable yields (up to 98%) with gratifying enantioselectivities (up to 98% ee) under mild conditions. To the best of our knowledge, it represents the first example in the ring-opening reactions of oxabicyclic alkenes with alkoxysilanes. Furthermore, the cis-1,2-configuration of product was established by X-ray diffraction analysis, and a possible mechanism for the present catalytic ring-opening reaction was also proposed. (Figure presented.).

Asymmetric Ring-Opening Reactions of Aza- and Oxa-bicyclic Alkenes with Boronic Acids Using a Palladium/Zinc Co-catalytic System

The asymmetric ring opening reactions of bicyclic alkenes with boronic acids were accomplished by using a highly active palladium/zinc co-catalytic system that was suitable for both azabenzonorbornadienes and oxabenzonorbornadienes, which were transformed to the corresponding chiral hydronaphthalene products in high yields (up to 99%) and high optical purities (up to 98% ee). The reaction protocol is general and mild and displays good functional group tolerance.