4269-97-0

Basic information

• Product Name: S-ISOPROPYLTHIOUREA HYDROBROMIDE
• Synonyms: ISOPROPYL CARBAMIMIDOTHIOATE, HYDROBROMIDE;IPTU;5-ISOPROPYLTHIURONIUM BROMIDE;S-ISOPROPYLISOTHIOUREA HYDROBROMIDE;S-ISOPROPYL ITU;S-ISOPROPYL-ITU HYDROBROMIDE;S-ISOPROPYLTHIOUREA HYDROBROMIDE;S-Isopropylthiourea hydrobromide, S-Isopropylthiuronium bromide
• CAS NO: 4269-97-0
• Molecular Formula: BrH*C₄H₁₀N₂S
• Molecular Weight: 199.11
• Mol File: 4269-97-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: 82-86 °C
• Appearance: /
• CAS DataBase Reference: S-ISOPROPYLTHIOUREA HYDROBROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: S-ISOPROPYLTHIOUREA HYDROBROMIDE(4269-97-0)
• EPA Substance Registry System: S-ISOPROPYLTHIOUREA HYDROBROMIDE(4269-97-0)

Safety Data

• Hazard Codes: Xi
• Statements: 37
• Safety Statements: 26-36
• RIDADR: UN 2923 8/PG 3
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 4269-97-0(Hazardous Substances Data)

Usage

Description

S-Isopropylthiourea Hydrobromide, also known as SIPTH, is a chemical compound with the molecular formula C7H14BrN3S. It is a white crystalline solid that is soluble in water and has been identified as a potent inhibitor of the isoform of nitric oxide synthase (iNOS). This characteristic makes it a valuable compound for research and potential therapeutic applications in various disease models.

Uses

Used in Pharmaceutical Research:
S-Isopropylthiourea Hydrobromide is used as a research chemical for studying the role of iNOS in various disease models. Its ability to inhibit iNOS makes it a valuable tool in understanding the underlying mechanisms of diseases associated with nitric oxide production, such as inflammation, cancer, and neurodegenerative disorders.
Used in Drug Development:
S-Isopropylthiourea Hydrobromide is used as a lead compound in the development of new drugs targeting iNOS. By inhibiting this enzyme, it may help in the treatment of conditions where excessive nitric oxide production contributes to the pathology of the disease. This application is particularly relevant in the development of therapeutics for inflammatory and autoimmune diseases, as well as certain types of cancer.
Used in Diagnostic Applications:
S-Isopropylthiourea Hydrobromide can be used as a diagnostic agent to identify the presence of iNOS in biological samples. This can be useful in the detection and monitoring of diseases where iNOS activity is elevated, providing valuable information for clinicians and researchers.

Downstream Products

• 22818-59-3 (isopropylthio)acetic acid