42729-22-6

Basic information

• Product Name: 2-{[3-(trifluoromethyl)phenyl]amino}isonicotinic acid
• Synonyms: 2-{[3-(trifluoromethyl)phenyl]amino}isonicotinic acid
• CAS NO: 42729-22-6
• Molecular Formula: C13H9F3N2O2
• Molecular Weight: 282.22
• Product Categories: Carboxylic Acids;Pyridines;Carboxylic Acids
• Mol File: 42729-22-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-{[3-(trifluoromethyl)phenyl]amino}isonicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[3-(trifluoromethyl)phenyl]amino}isonicotinic acid(42729-22-6)
• EPA Substance Registry System: 2-{[3-(trifluoromethyl)phenyl]amino}isonicotinic acid(42729-22-6)

Safety Data

• Hazardous Substances Data: 42729-22-6(Hazardous Substances Data)

Usage

General Description

2-{[3-(trifluoromethyl)phenyl]amino}isonicotinic acid, also known as TAPIA, is a chemical compound with potential applications in the pharmaceutical and agrochemical industries. It consists of a substituted isonicotinic acid core with a trifluoromethylphenylamino group attached at the 2-position. 2-{[3-(trifluoromethyl)phenyl]amino}isonicotinic acid has been explored for its potential as an antimicrobial and antifungal agent, as well as for its ability to inhibit certain enzymes involved in disease processes. TAPIA has also shown promise as a building block in the synthesis of complex molecules for drug discovery and development. The trifluoromethyl group is known to confer enhanced biological activity and metabolic stability to molecules, making TAPIA an interesting target for further research and development in the field of medicinal chemistry.

Upstream product

• 58481-11-1 methyl 2-chloroisonicotinate 
• 98-16-8 3-trifluoromethylaniline 

Relevant articles and documents

SOME NEW DERIVATIVES OF 4-PYRIDINECARBOXYLIC ACIDS. PART I. PRODUCTS OF REACTIONS WITH AROMATIC AMINES.

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