42754-54-1

Basic information

• Product Name: 3,4-diamino-4'-chlorobenzophenone
• Synonyms: 3,4-diamino-4'-chlorobenzophenone
• CAS NO: 42754-54-1
• Molecular Weight: 246.696
• Mol File: 42754-54-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,4-diamino-4'-chlorobenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-diamino-4'-chlorobenzophenone(42754-54-1)
• EPA Substance Registry System: 3,4-diamino-4'-chlorobenzophenone(42754-54-1)

Safety Data

• Hazardous Substances Data: 42754-54-1(Hazardous Substances Data)

Upstream product

• 1285819-56-8 4-azido-4'-chloro-3-nitrobenzophenone 
• 90-98-2 4,4'-Dichlorobenzophenone 
• 31431-17-1 4,4'-dichloro-3-nitrobenzophenone 
• 31431-27-3 (4-amino-3-nitrophenyl)-(4-chlorophenyl)-methanone 

Downstream Products

• 1285819-57-9 4'-chloro-3,4-di(tert-butoxycarbonylamino)benzophenone 
• 1285819-64-8 (R)-6-((4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl)-1H-benzo[d][1,2,3]-triazole 
• 1285819-60-4 4-(chloro(4-chlorophenyl)methyl)-1,2-di(tert-butoxycarbonylamino)benzene 
• 1285819-59-1 (3,4-bis(tert-butoxycarbonylamino)phenyl)(4-chlorophenyl)methyl methanesulfonate 
• 1285819-58-0 4'-chloro-3,4-di(tert-butoxycarbonylamino)benzhydrol 
• 1285819-62-6 4-{(4-chlorophenyl)(4H-1,2,4-triazol-4-yl)methyl}-1,2-di(tert-butoxycarbonylamino)benzene 
• 1285819-61-5 4-{(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl}-1,2-di(tert-butoxycarbonylamino)benzene 
• 854534-81-9 1,2-diamino-4-{(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)-methyl}benzene 
• 247153-23-7 6-{(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl}-1H-benzo[d][1,2,3]triazole 

Relevant articles and documents

Practical synthesis of precursor of [N-methyl-11C]vorozole, an efficient PET tracer targeting aromatase in the brain

A practical method to prepare precursor of [N-methyl-11C] vorozole ([11C]vorozole), an efficient positron emission tomography (PET) tracer for imaging aromatase in the living body, was established. Sufficient amount of the racemate including norvorozole, a demethylated vorozole derivative used as a precursor of [11C]vorozole, became available by means of high-yield eight-step synthesis. The enantiomers were separated by preparative HPLC using a chiral stationary phase column to give optically pure norvorozole and its enantiomer. From the latter, ent-[11C]vorozole, an enantiomer of [11C]vorozole, was prepared and used in the PET study for the first time, which was shown to bind very weakly to aromatase in rhesus monkey brain supporting the previous pharmacological results. The stable supply of norvorozole will facilitate further researches on aromatase in the living body including brain by the PET technique.