42785-81-9 Usage
Description
1-(2-METHYLBUT-3-YN-2-YL)-3-PHENYLUREA is a chemical compound with the molecular formula C12H14N2O, featuring a urea group (NH2CONH2) with a phenyl group and a 2-methylbut-3-yn-2-yl group attached to the nitrogen atoms. 1-(2-METHYLBUT-3-YN-2-YL)-3-PHENYLUREA holds potential in medicinal chemistry and pharmaceutical research due to its unique structural features, which may lead to novel biological activities. It can also serve as a building block for synthesizing more complex organic molecules. Caution is advised when handling this chemical, as some properties and potential hazards are not yet well-documented.
Uses
Used in Pharmaceutical Research:
1-(2-METHYLBUT-3-YN-2-YL)-3-PHENYLUREA is used as a compound in pharmaceutical research for its potential unique biological activity, which may contribute to the development of new medications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(2-METHYLBUT-3-YN-2-YL)-3-PHENYLUREA is used as a structural component for designing and synthesizing new molecules with therapeutic potential.
Used in Organic Synthesis:
1-(2-METHYLBUT-3-YN-2-YL)-3-PHENYLUREA is used as a building block in organic synthesis for creating more complex organic molecules with various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 42785-81-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,7,8 and 5 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 42785-81:
(7*4)+(6*2)+(5*7)+(4*8)+(3*5)+(2*8)+(1*1)=139
139 % 10 = 9
So 42785-81-9 is a valid CAS Registry Number.
42785-81-9Relevant articles and documents
Synthesis of Imidazolidin-2-ones and Imidazol-2-ones via Base-Catalyzed Intramolecular Hydroamidation of Propargylic Ureas under Ambient Conditions
Casnati, Alessandra,Perrone, Antonio,Mazzeo, Paolo P.,Bacchi, Alessia,Mancuso, Raffaella,Gabriele, Bartolo,Maggi, Raimondo,Maestri, Giovanni,Motti, Elena,Stirling, András,Ca, Nicola Della
, p. 3477 - 3490 (2019/03/11)
The first organo-catalyzed synthesis of imidazolidin-2-ones and imidazol-2-ones via intramolecular hydroamidation of propargylic ureas is reported. The phosphazene base BEMP turned out to be the most active organo-catalyst compared with guanidine and amidine bases. Excellent chemo- and regioselectivities to five-membered cyclic ureas have been achieved under ambient conditions, with a wide substrate scope and exceptionally short reaction times (down to 1 min). A base-mediated isomerization step to an allenamide intermediate is the most feasible reaction pathway to give imidazol-2-ones, as suggested by DFT studies.
