4280-43-7

Basic information

• Product Name: Benzamide,N,N'-(4-methoxy-1,2-phenylene)bis- (9CI)
• Synonyms: Benzamide,N,N'-(4-methoxy-o-phenylene)bis- (6CI,7CI,8CI); NSC 29126
• CAS NO: 4280-43-7
• Molecular Formula: C21H18 N2 O3
• Molecular Weight: 346.386
• Mol File: 4280-43-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 390.3°Cat760mmHg
• Flash Point: 189.8°C
• Density: 1.277g/cm³
• CAS DataBase Reference: Benzamide,N,N'-(4-methoxy-1,2-phenylene)bis- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide,N,N'-(4-methoxy-1,2-phenylene)bis- (9CI)(4280-43-7)
• EPA Substance Registry System: Benzamide,N,N'-(4-methoxy-1,2-phenylene)bis- (9CI)(4280-43-7)

Safety Data

• Hazardous Substances Data: 4280-43-7(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 
• 102-51-2 4-methoxy-1,2-phenylenediamine 
• 98-88-4 benzoyl chloride 
• 744-38-7 1,2-dibenzamidobenzene 
• 96-96-8 4-methoxy-2-nitroaniline 
• 67-56-1 methanol 
• 54748-01-5 N,N'-3,5-cyclohexadiene-1,2-diylidenebis(benzamide) 

Relevant articles and documents

Regioselective Synthesis of Trisubstituted Quinoxalines Mediated by Hypervalent Iodine Reagents

A facile and regioselective synthesis of quinoxalines, an important motif in medicinal chemistry and materials sciences, was developed. Despite their prospective utility, the regioselective preparation of trisubstituted quinoxalines has not been previously established. In the reported system, hypervalent iodine reagents catalyzed the annulation between α-iminoethanones ando-phenylenediamines in a chemo/regioselective manner to afford trisubstituted quinoxalines. Excellent regioselectivities (6:1 to 1:0) were achieved using [bis(trifluoroacetoxy)iodo]benzene and [bis(trifluoroacetoxy)iodo]pentafluorobenzene as annulation catalysts.