42801-36-5

Basic information

• Product Name: 1,3,2',6'-tetrakis-N-benzyloxycarbonylgentamine C_1a
• Synonyms: 1,3,2',6'-tetrakis-N-benzyloxycarbonylgentamine C_1a
• CAS NO: 42801-36-5
• Molecular Weight: 826.901
• Mol File: 42801-36-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3,2',6'-tetrakis-N-benzyloxycarbonylgentamine C_1a(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,2',6'-tetrakis-N-benzyloxycarbonylgentamine C_1a(42801-36-5)
• EPA Substance Registry System: 1,3,2',6'-tetrakis-N-benzyloxycarbonylgentamine C_1a(42801-36-5)

Safety Data

• Hazardous Substances Data: 42801-36-5(Hazardous Substances Data)

Upstream product

• 35025-95-7 (1S,2R,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(aminomethyl)tetrahydropyran-2-yl]oxy-cyclohexane-1,2-diol 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 34493-98-6 dibecacin 
• 56153-88-9 O-3-deoxy-3-methylamino-β-L-arabinopyranosyl-(1->6)-gentamine C_1a 
• 918301-93-6 C₅₂H₆₄N₆O₁₅ 
• 918301-92-5 C₅₂H₆₄N₆O₁₅ 
• 918301-91-4 C₄₂H₅₀N₄O₁₃ 
• 918302-00-8 C₄₁H₅₂N₄O₁₂ 
• 918301-95-8 C₅₃H₆₆N₆O₁₅ 
• 918301-94-7 C₅₃H₆₆N₆O₁₅ 
• 79248-85-4 O-2,4-di-O-benzyl-3-deoxy-3-N-methylacetamido-β-L-arabinopyranosyl-(1->6)-1,3,2',6'-tetrakis-N-benzyloxycarbonylgentamine C_1a 

Relevant articles and documents

Semisynthetic Aminoglycoside Antibacterials. Part 7. Synthesis of Novel Hexopyranosyl and Hexofuranosyl Derivatives of Gentamine C1 and C1a

Acidic hydrolysis of gentamicin C1 and C1a provides ready access to the pseudodisaccharides gentamine C1 and C1a respectively.Glycosylation of tetrakis-N-benzyloxycarbonylgentamine C1 and C1a using the Koenigs-Knorr or Lemieux-Nagabhushan reactions has led to the preparation of a series of novel 6-O-α- and -β-3-amino-3-deoxy- and 2-amino-2-deoxy-D-hexopyranosyl and hexofuranosyl analogues of the gentamicins.The 13C n.m.r. properties of representative compounds are described and the rotamer populations about the C-4-O and C-6-O glycosidic bonds are discussed.