4284-50-8

Basic information

• Product Name: N-(4-BROMOPHENYL)METHANESULFONAMIDE, 97%
• Synonyms: N-(4-BROMOPHENYL)METHANESULFONAMIDE, 97%;N-(4-Bromophenyl)methansulfonamide;Methansulfonic acid-(4-bromoanilide);4-(Methylsulfonylamido)bromobenzene;4'-BroMoMethanesulfonanilide;Methanesulfonanilide, 4'-broMo- (6CI,7CI,8CI);N-(4-BroMophenyl)MethanesulfonaMide 97%;N-(4-BROMOPHENYL)METHANESULFONAMIDE-2
• CAS NO: 4284-50-8
• Molecular Formula: C₇H₈BrNO₂S
• Molecular Weight: 250.11292
• Product Categories: Aryl;Organohalides;Organoborons
• Mol File: 4284-50-8.mol
• Article Data: 38

Chemical Properties

• Melting Point: 137-141 °C
• Boiling Point: 333°C at 760 mmHg
• Flash Point: 155.2°C
• Appearance: /
• Density: 1.711g/cm³
• Vapor Pressure: 0.000141mmHg at 25°C
• Refractive Index: 1.623
• CAS DataBase Reference: N-(4-BROMOPHENYL)METHANESULFONAMIDE, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-BROMOPHENYL)METHANESULFONAMIDE, 97%(4284-50-8)
• EPA Substance Registry System: N-(4-BROMOPHENYL)METHANESULFONAMIDE, 97%(4284-50-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 4284-50-8(Hazardous Substances Data)

Usage

General Description

N-(4-bromophenyl)methanesulfonamide is a chemical compound with a purity level of 97%. It is an organosulfur compound that contains a bromine atom and a sulfonamide group. This chemical is often used as a pharmaceutical intermediate in the synthesis of various pharmaceutical products. It may also be utilized as a reagent for the preparation of other organic compounds. Additionally, it has potential applications in the field of medicinal chemistry and drug discovery. With a high purity level of 97%, this compound is suitable for use in research and development, as well as in industrial processes that require high-quality chemicals.

InChI:InChI=1/C7H8BrNO2S/c1-12(10,11)9-7-4-2-6(8)3-5-7/h2-5,9H,1H3

Upstream product

• 1197-22-4 N-phenylmethanesulfonamide 
• 124-63-0 methanesulfonyl chloride 
• 106-40-1 4-bromo-aniline 
• 191043-81-9 N-(4-bromophenyl)-N-(methylsulfonyl)methanesulfonamide 
• 5467-74-3 4-Bromophenylboronic acid 
• 624-90-8 Methanesulfonyl azide 
• 75-75-2 methanesulfonic acid 
• 62-53-3 aniline 
• 7143-01-3 Methanesulfonic anhydride 

Downstream Products

• 22729-44-8 N-(4-Bromo-phenyl)-N-(1,1,2,2-tetrachloro-2-fluoro-ethylsulfanyl)-methanesulfonamide 
• 344439-21-0 N-(4-Bromo-phenyl)-N-[1,3]dioxolan-2-ylmethyl-methanesulfonamide 
• 88131-50-4 N-(4-Bromo-phenyl)-N-(2,2-diethoxy-ethyl)-methanesulfonamide 
• 333383-76-9 N-(4-bromo-phenyl)-N-(3-oxo-propyl)-methanesulfonamide 
• 879403-80-2 1-[((4-bromophenyl)(methylsulfonyl)amino)methyl]-2-chlorobenzene 
• 5332-25-2 6-bromoquinoline 
• 10075-50-0 5-bromo-1H-indole 
• 99980-38-8 N-(4-bromophenyl)-N-methylmethanesulfonamide 
• 301308-88-3 N-(4-ethylphenyl)methanesulfonamide 
• 616880-14-9 N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanesulfonamide 
• 1296307-26-0 N-methyl-N-(4-(6-(1-methyl-1H-pyrazol-4-ylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)methanesulfonamide 
• 1246375-61-0 C₂₄H₃₀N₂O₄S 
• 1246375-05-2 N-hydroxy-7-(N-(4-(1-methyl-1H-indol-5-yl)phenyl)methylsulfonamido)heptanamide 
• 1246375-60-9 C₁₆H₂₄BrNO₄S 

Relevant articles and documents

Meta Selective C-H Borylation of Sterically Biased and Unbiased Substrates Directed by Electrostatic Interaction

An electrostatically directed meta borylation of sterically biased and unbiased substrates is described. The borylation follows an electrostatic interaction between the partially positive and negative charges between the ligand and substrate. With this strategy, it has been demonstrated that a wide number of challenging substrates, especially 4-substituted substrates, can selectively be borylated at the meta position. Moreover, unsubstituted substrates also displayed excellent meta selectivity. The reaction employs a bench-stable ligand and proceeds at a milder temperature, precluding the need to synthesize a bulky and sophisticated ligand/template.

Facile Chan-Lam coupling using ferrocene tethered N-heterocyclic carbene-copper complex anchored on graphene

Ferrocene tethered N-heterocyclic carbene-copper complex anchored on graphene ([GrFemImi]NHC@Cu complex) has been synthesized by covalent grafting of ferrocenyl ionic liquid in the matrix of graphene followed by metallation with copper (I) iodide. The [GrFemImi]NHC@Cu complex has been characterized by fourier transform infrared (FT-IR), fourier transform Raman (FT-Raman), CP-MAS 13C NMR spectroscopy, transmission electron microscopy (TEM), thermogravimetric analysis (TGA), energy dispersive X-ray (EDX) analysis, X-ray photoelectron spectroscopy (XPS), Brunauer–Emmett–Teller (BET) surface area analysis and X-ray diffractometer (XRD) analysis. This novel complex served as a robust heterogeneous catalyst for the synthesis of bioactive N-aryl sulfonamides from variety of aryl boronic acids and sulfonyl azides in ethanol by Chan-Lam coupling. Recyclability experiments were executed successfully for six consecutive runs.

Continuous-Flow Electrosynthesis of Benzofused S-Heterocycles by Dehydrogenative C?S Cross-Coupling

Reported herein is the synthesis of benzofused six-membered S-heterocycles by intramolecular dehydrogenative C?S coupling using a modular flow electrolysis cell. The continuous-flow electrosynthesis not only ensures efficient product formation, but also obviates the need for transition-metal catalysts, oxidizing reagents, and supporting electrolytes. Reaction scale-up is conveniently achieved through extended electrolysis without changing the reaction conditions and equipment.