428518-38-1

Basic information

• Product Name: 3-Pyrrolidinecarboxylicacid,1-ethyl-5-oxo-,(3S)-(9CI)
• Synonyms: 3-Pyrrolidinecarboxylicacid,1-ethyl-5-oxo-,(3S)-(9CI)
• CAS NO: 428518-38-1
• Molecular Formula: C7H11NO3
• Molecular Weight: 157.17
• Product Categories: CARBOXYLICACID
• Mol File: 428518-38-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Pyrrolidinecarboxylicacid,1-ethyl-5-oxo-,(3S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyrrolidinecarboxylicacid,1-ethyl-5-oxo-,(3S)-(9CI)(428518-38-1)
• EPA Substance Registry System: 3-Pyrrolidinecarboxylicacid,1-ethyl-5-oxo-,(3S)-(9CI)(428518-38-1)

Safety Data

• Hazardous Substances Data: 428518-38-1(Hazardous Substances Data)

Upstream product

• 617-52-7 Dimethyl itakonate 
• 100911-29-3 methyl 1-ethyl-5-oxo-3-pyrrolidinecarboxylate 
• 97-65-4 2-methylenesuccinic acid 
• 75-04-7 ethylamine 

Relevant articles and documents

AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS

The present invention relates to compounds of Formula (I), their synthesis and use as CCR6 receptor modulators for the treatment or prevention of various diseases, conditions or disorders.

THIAZOLE DERIVATIVE

Provided is a compound having an agonist action on GPR52, which is useful as a prophylactic or therapeutic drug for mental diseases such as schizophrenia and the like, and the like. A compound represented by the formula (I): wherein each symbol is as defi

A chemoenzymatic approach to the synthesis of enantiomerically pure aza analogues of paraconic acid methyl ester and both enantiomers of methyl β-proline

Enantiopure methyl esters of 1-alkyl-5-oxo-3-pyrrolidinecarboxylic acids were obtained by enzymatic resolution of the corresponding chiral racemic mixtures. A particularly favourable interaction, also supported by molecular mechanics calculations, was observed between the 1-benzyl derivative and α-chymotrypsin, for which the enantiomeric ratio, E, exceeded 200. The absolute configurations of the lactams were determined by means of CD spectroscopy. From the resulting enantiomerically pure (99% e.e.) (S)-(+)-1-benzyl-3-pyrrolidinecarboxylic acid and methyl (R)-(-)-1-benzyl-3-pyrrolidinecarboxylate, the methyl esters of (+) and (-)-β-proline were synthesised in 99% e.e. and 18 and 22% overall yield, respectively.