42869-47-6 Usage
General Description
6-Bromo-2-methyl-4H-imidazo[4,5-b]pyridine is a chemical compound with the molecular formula C8H6BrN3. It is a heterocyclic compound with a pyridine ring fused to an imidazole ring, containing a bromine atom at the 6-position and a methyl group at the 2-position. 6-BROMO-2-METHYL-4H-IMIDAZO[4,5-B]PYRIDINE is primarily used in the pharmaceutical industry as a building block for the synthesis of various bioactive molecules, such as kinase inhibitors and antiviral drugs. It has also been studied for its potential applications in the field of medicinal chemistry and drug discovery. Additionally, 6-Bromo-2-methyl-4H-imidazo[4,5-b]pyridine is known for its biological activity as a GABAA receptor modulator, which contributes to its pharmacological interest.
Check Digit Verification of cas no
The CAS Registry Mumber 42869-47-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,8,6 and 9 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 42869-47:
(7*4)+(6*2)+(5*8)+(4*6)+(3*9)+(2*4)+(1*7)=146
146 % 10 = 6
So 42869-47-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H6BrN3/c1-4-10-6-2-5(8)3-9-7(6)11-4/h2-3H,1H3,(H,9,10,11)
42869-47-6Relevant articles and documents
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Petrow,Saper
, p. 1389,1392 (1948)
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Heterocyclisation via Selective Elimination: Reaction of 2,3-Diaminopyridine with Acyclic Ketones under Thermal Conditions
Dubey, Pramod Kumar,Ratnam, C. V.
, p. 863 - 865 (2007/10/02)
Reactions of 2,3-diaminopyridine and its 5-bromo analogue with three symmetrical and nine unsymmetrical acyclic ketones under thermal conditions have been studied.The reactions have yielded 2-substituted-1H-imidazopyridines by the elimination of one of the C2-substituents from the probable, though unisolated, intermediates 2,2-disubstituted-2,3-dihydro-1H-imidazopyridine derivatives.Elimination of one of the groups in the case of symmetrical ketones and preferentially of benzyl group in the case of benzyl methyl ketone has been observed.All the three alkyl phenyl ketones studied afford 2-phenylimidazopyridine by the selective loss of the alkyl group.Elimination of branched alkyl group has been noticed in the reactions involving methyl t-butyl and methyl i-propyl ketones, while the preferential elimination of methyl group is observed in the case of methyl n-alkyl ketones.Suitable explanations have been offered for the observed selective eliminations.