428880-36-8

Basic information

• Product Name: [8-(tert-butoxycarbonyl-{6-[tert-butoxycarbonyl-(5-iodo-2-methoxybenzyl)amino]hexyl}amino)octyl]-(6-{tert-butoxycarbonyl-[3-(2,2,2-trifluoroacetylamino)propyl]amino}hexyl)carbamic acid tert-butyl ester
• Synonyms: [8-(tert-butoxycarbonyl-{6-[tert-butoxycarbonyl-(5-iodo-2-methoxybenzyl)amino]hexyl}amino)octyl]-(6-{tert-butoxycarbonyl-[3-(2,2,2-trifluoroacetylamino)propyl]amino}hexyl)carbamic acid tert-butyl ester
• CAS NO: 428880-36-8
• Molecular Weight: 1142.23
• Mol File: 428880-36-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [8-(tert-butoxycarbonyl-{6-[tert-butoxycarbonyl-(5-iodo-2-methoxybenzyl)amino]hexyl}amino)octyl]-(6-{tert-butoxycarbonyl-[3-(2,2,2-trifluoroacetylamino)propyl]amino}hexyl)carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [8-(tert-butoxycarbonyl-{6-[tert-butoxycarbonyl-(5-iodo-2-methoxybenzyl)amino]hexyl}amino)octyl]-(6-{tert-butoxycarbonyl-[3-(2,2,2-trifluoroacetylamino)propyl]amino}hexyl)carbamic acid tert-butyl ester(428880-36-8)
• EPA Substance Registry System: [8-(tert-butoxycarbonyl-{6-[tert-butoxycarbonyl-(5-iodo-2-methoxybenzyl)amino]hexyl}amino)octyl]-(6-{tert-butoxycarbonyl-[3-(2,2,2-trifluoroacetylamino)propyl]amino}hexyl)carbamic acid tert-butyl ester(428880-36-8)

Safety Data

• Hazardous Substances Data: 428880-36-8(Hazardous Substances Data)

Upstream product

• 428880-31-3 {8-[tert-butoxycarbonyl-(6-tert-butoxycarbonylaminohexyl)amino]octyl}-{6-[tert-butoxycarbonyl-(2-cyanoethyl)amino]hexyl}carbamic acid tert-butyl ester 
• 428880-32-4 {6-[(3-aminopropyl)-tert-butoxycarbonylamino]hexyl}-{8-[tert-butoxycarbonyl-(6-tert-butoxycarbonylaminohexyl)amino]octyl}carbamic acid tert-butyl ester 
• 428879-87-2 {8-[(6-aminohexyl)-tert-butoxycarbonylamino]octyl}-(6-tert-butoxycarbonylaminohexyl)carbamic acid tert-butyl ester 
• 104807-24-1 N,N'-bis(6-aminohexyl)-1,8-octanediamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 428880-35-7 2,2,2-trifluoro-N-[3-(6-{8-[6-(5-iodo-2-methoxybenzylamino)hexylamino]octylamino}hexylamino)propyl]acetamide 
• 42298-41-9 5-iodo-2-methoxy-benzaldehyde 
• 428880-34-6 N-(3-{6-[8-(6-aminohexylamino)octylamino]hexylamino}propyl)-2,2,2-trifluoroacetamide 

Downstream Products

• 428880-38-0 [8-(tert-butoxycarbonyl-{6-[tert-butoxycarbonyl-(5-iodo-2-methoxybenzyl)amino]hexyl}amino)octyl]-[6-(tert-butoxycarbonyl-{3-[(7-methoxy-2-oxo-2H-chromene-3-carbonyl)amino]propyl}amino)hexyl]carbamic acid tert-butyl ester 
• 428880-37-9 {6-[(3-aminopropyl)-tert-butoxycarbonylamino]hexyl}-[8-(tert-butoxycarbonyl-{6-[tert-butoxycarbonyl-(5-iodo-2-methoxybenzyl)amino]hexyl}amino)octyl]carbamic acid tert-butyl ester 

Relevant articles and documents

Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 2. Role of polymethylene chain lengths separating amine functions and of substituents on the terminal nitrogen atoms

Polymethylene tetraamine methoctramine (1) is a prototypical antimuscarinic ligand endowed with a significant affinity for muscular nAChRs. Thus, according to the universal template approach, structural modifications were performed on 1 in order to improv