42902-32-9

Basic information

• Product Name: 5-HYDROXYMETHYL-3-(4-METHOXYPHENYL)-2-OXAZOLIDINONE
• Synonyms: 5-hydroxymethyl-3-(p-methoxyphenyl)-2-oxazolidinon;5-HYDROXYMETHYL-3-(4-METHOXYPHENYL)-2-OXAZOLIDINONE;cytoxazone;5-Hydroxymethyl-3-(4-methoxy-phenyl)-oxazolidin-2-one;5-Hydroxymethyl-3-(p-methoxyphenyl)oxazolidin-2-one
• CAS NO: 42902-32-9
• Molecular Formula: C₁₁H₁₃NO₄
• Molecular Weight: 223.23
• Product Categories: pharmacetical
• Mol File: 42902-32-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 139-140 °C(Solv: ethanol (64-17-5))
• Boiling Point: 385.3°C at 760 mmHg
• Flash Point: 186.8°C
• Appearance: /
• Density: 1.282g/cm³
• Vapor Pressure: 1.26E-06mmHg at 25°C
• Refractive Index: 1.562
• PKA: 14.05±0.10(Predicted)
• CAS DataBase Reference: 5-HYDROXYMETHYL-3-(4-METHOXYPHENYL)-2-OXAZOLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-HYDROXYMETHYL-3-(4-METHOXYPHENYL)-2-OXAZOLIDINONE(42902-32-9)
• EPA Substance Registry System: 5-HYDROXYMETHYL-3-(4-METHOXYPHENYL)-2-OXAZOLIDINONE(42902-32-9)

Safety Data

• Hazardous Substances Data: 42902-32-9(Hazardous Substances Data)

Usage

General Description

5-HYDROXYMETHYL-3-(4-METHOXYPHENYL)-2-OXAZOLIDINONE is a chemical compound that belongs to the oxazolidinone class. It is a heterocyclic compound with a five-membered ring containing oxygen and nitrogen atoms. The presence of a hydroxymethyl group and a 4-methoxyphenyl group in its structure gives it unique properties and potential applications. Oxazolidinones have been studied for their antibacterial, antifungal, and antiviral activities, and 5-HYDROXYMETHYL-3-(4-METHOXYPHENYL)-2-OXAZOLIDINONE may have similar bioactive properties. Further research is needed to fully understand its potential applications and effects.

InChI:InChI=1/C11H13NO4/c1-15-9-4-2-8(3-5-9)12-6-10(7-13)16-11(12)14/h2-5,10,13H,6-7H2,1H3

Upstream product

• 121082-77-7 3-<(4-methoxyphenyl)amino>-1,2-propanediol 
• 105-58-8 Diethyl carbonate 
• 616-38-6 carbonic acid dimethyl ester 
• 104-94-9 4-methoxy-aniline 
• 124-38-9 carbon dioxide 
• 3470-93-7 1-chloro-3-[(4-methoxyphenyl)amino]propan-2-ol 

Downstream Products

• 42902-46-5 5-carbamoyloxymethyl-3-(4-methoxy-phenyl)-oxazolidin-2-one 
• 121082-79-9 5-(Chloromethyl)-3-(4-methoxyphenyl)-2-oxazolidinone 
• 121082-86-8 5-(Bromomethyl)-3-(4-methoxyphenyl)-2-oxazolidinone 
• 121082-76-6 5-(methanesulfonyloxymethyl)-3-p-methoxyphenyl-2-oxazolidinone 
• 27125-11-7 5-<(N,N-dimethylamino)methyl>-3-(4-methoxyphenyl)-2-oxazolidinone 
• 130641-87-1 3-(4-methoxyphenyl)-5-<(N-methylamino)methyl>-2-oxazolidinone 
• 71954-46-6 N-allyl-4-methoxyaniline 
• 121485-50-5 3-(4-Methoxyphenyl)-5-methyl-2-oxazolidinone 
• 148915-85-9 5-(aminomethyl)-3-(4-methoxyphenyl)-2-oxazolidinone 

Relevant articles and documents

Switchable synthesis of cyclic carbamates by carbon dioxide fixation at atmospheric pressure

The base-promoted switchable synthesis of five- and six-membered cyclic carbamates using atmospheric pressure carbon dioxide as the C1 source was developed. The chemoselectivity of products was simply controlled by changing bases and solvents. The reaction proceeds effectively under mild conditions, affording valuable cyclic carbamates. Experimental results and DFT studies revealed the reaction mechanism.

Transformation of heterocyclic reversible monoamine oxidase-B inactivators into irreversible inactivators by N-methylation

3-[4-[(3-Chlorophenyl)methoxy]phenyl]-5-[(methylamino)methyl]-2- oxazolidinone (1) is a secondary amine known to be a potent time-dependent irreversible inactivator of monoamine oxidase B (MAO-B). The primary amine analogues of derivatives of 1, as well a

A new series of antidepressants: derivatives of 5 hydroxymethyl 2 oxazolidinone. I. Synthesis

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