42921-37-9Relevant articles and documents
Synthesis and Antitumor Activity of Dehydroepiandrosterone Derivatives on Es-2, A549, and HepG2 Cells in vitro
Liu, Xue-Kun,Ye, Bai-Jun,Wu, Yan,Nan, Ji-Xing,Lin, Zhen-Hua,Piao, Hu-Ri
, p. 523 - 529 (2012/06/15)
A series of dehydroepiandrosterone derivatives containing an acid ester was synthesized and evaluated for their antitumor activity on ES-2, A549, and HepG2 cells by the MTT assay. Most compounds showed antitumor activity, while compounds 1c, 2i, and 2o exhibited more potential inhibitory effects compared with dehydroepiandrosterone on ES-2 cells, A549 cells, and HepG2 cells, respectively.