429672-02-6 Usage
Description
1-Boc-3-azido-azetidine is a chemical compound that features a Boc-protected azetidine ring with an azido group at the 3-position. It is a versatile building block in organic synthesis and has potential applications in the pharmaceutical industry due to its unique structural features.
Uses
Used in Pharmaceutical Industry:
1-Boc-3-azido-azetidine is used as a reactant for the preparation of cyanoazetidines, cyanopyrrolidines, and their analogs. These compounds serve as inhibitors of cathepsin, an enzyme family involved in various physiological processes, including protein degradation and immune response. By inhibiting cathepsin, these compounds can potentially be used in the treatment of various diseases, such as cancer and autoimmune disorders.
Additionally, 1-Boc-3-azido-azetidine and its derivatives can be used as antiosteoporotic agents. Osteoporosis is a bone disease characterized by low bone mass and increased bone fragility, leading to a higher risk of fractures. 1-Boc-3-azido-azetidines derived from 1-Boc-3-azido-azetidine may help in the development of new therapeutic strategies to combat osteoporosis by targeting specific pathways involved in bone metabolism and maintaining bone health.
Check Digit Verification of cas no
The CAS Registry Mumber 429672-02-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,2,9,6,7 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 429672-02:
(8*4)+(7*2)+(6*9)+(5*6)+(4*7)+(3*2)+(2*0)+(1*2)=166
166 % 10 = 6
So 429672-02-6 is a valid CAS Registry Number.
429672-02-6Relevant articles and documents
PROTEIN TYROSINE PHOSPHATASE DEGRADERS AND METHODS OF USE THEREOF
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, (2021/06/26)
Provided herein are compounds, compositions, and methods useful for degrading protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer 5 or a metabolic disease.
CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY
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Page/Page column 77, (2012/01/06)
The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.
N-HETEROCYCLYL-SUBSTITUTED AMINO-THIAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS
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Page 39; 40, (2010/02/08)
Aminothiazole compounds with N-containing cycloalkyl at the 2-amino position which are represented by the Formula (I), or a pharmaceutically acceptable prodrug of said compound, or pharmaceutically acceptable salt of said compound, modulate and/or inhibit the cell proliferation and activity of protein kinases.
