4300-43-0 Usage
Description
N,N′-BIS-(3,4-DICHLOROPHENYL)UREA, also known as 3,3',4,4'-Tetrachlorocarbanilide, is an organic compound with the molecular formula C13H8Cl2N2O2. It is a chlorocarbanilide co-contaminant found in US aquatic environments. N,N′-BIS-(3,4-DICHLOROPHENYL)UREA is characterized by its chlorine atoms attached to the phenyl rings and the urea group, which may contribute to its potential applications and properties.
Uses
Used in Environmental Monitoring:
N,N′-BIS-(3,4-DICHLOROPHENYL)UREA is used as a monitoring agent for assessing the presence and levels of chlorocarbanilide co-contaminants in aquatic environments. The detection and quantification of this compound can help in understanding the extent of pollution and the need for remediation efforts.
Used in Chemical Research:
In the field of chemical research, N,N′-BIS-(3,4-DICHLOROPHENYL)UREA serves as a starting material or intermediate for the synthesis of various chemical compounds, particularly those involving chlorinated aromatic rings and urea derivatives. Its unique structure makes it a valuable component in the development of new molecules with potential applications in various industries.
Used in Pesticide Formulation:
N,N′-BIS-(3,4-DICHLOROPHENYL)UREA is used as an active ingredient in the formulation of certain pesticides, specifically those targeting agricultural pests. Its chlorinated phenyl and urea functionalities may contribute to its pesticidal properties, making it a valuable component in the development of effective pest control solutions.
Used in Pharmaceutical Development:
Due to its unique chemical structure, N,N′-BIS-(3,4-DICHLOROPHENYL)UREA may have potential applications in the pharmaceutical industry as a starting material for the development of new drugs. Its properties, such as the presence of chlorine atoms and the urea group, could be exploited to design molecules with specific therapeutic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 4300-43-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,0 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4300-43:
(6*4)+(5*3)+(4*0)+(3*0)+(2*4)+(1*3)=50
50 % 10 = 0
So 4300-43-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H8Cl4N2O/c14-9-3-1-7(5-11(9)16)18-13(20)19-8-2-4-10(15)12(17)6-8/h1-6H,(H2,18,19,20)
4300-43-0Relevant articles and documents
QSAR and classification of murine and human soluble epoxide hydrolase inhibition by urea-like compounds
McElroy, Nathan R.,Jurs, Peter C.,Morisseau, Christophe,Hammock, Bruce D.
, p. 1066 - 1080 (2003)
A data set of 348 urea-like compounds that inhibit the soluble epoxide hydrolase enzyme in mice and humans is examined. Compounds having IC50 values ranging from 0.06 to >500 μM (murine) and 0.10 to >500 μM (human) are categorized as active or
N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation
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Page/Page column 116; 120, (2016/09/26)
Compositions and methods for inhibiting translation initiation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using N,N′-diarylureas and/or N,N′-diarylthiourea compounds are described.
A simple and efficient synthesis of diaryl ureas with reduction of the intermediate isocyanate by triethylamine
Zhou, Shuguang,Yao, Ting,Yi, Jicheng,Li, Dashuai,Xiong, Jing
, p. 315 - 319 (2013/07/27)
Thirty symmetrical diaryl urea derivatives were synthesised in moderate to excellent yields from arylamine and triphosgene with triethylamine as a reducing agent for the intermediate, isocyanate. It was significant that part of the products could be collected in almost quantitative yield without column chromatography. The procedure under mild reaction conditions was tolerant of a wide range of functional groups. The structures of the compounds were determined by NMR, MS and X-ray crystallographic analyses.