43029-26-1

Basic information

• Product Name: 7-(4-methoxy-phenyl)-3-methyl-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
• CAS NO: 43029-26-1
• Molecular Weight: 274.303
• Mol File: 43029-26-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 7-(4-methoxy-phenyl)-3-methyl-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(4-methoxy-phenyl)-3-methyl-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one(43029-26-1)
• EPA Substance Registry System: 7-(4-methoxy-phenyl)-3-methyl-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one(43029-26-1)

Safety Data

• Hazardous Substances Data: 43029-26-1(Hazardous Substances Data)

Upstream product

• 59758-48-4 2-{[5-(4-methoxy-phenyl)-[1,3,4]thiadiazol-2-yl]-hydrazono}-propionic acid 
• 57709-54-3 2-bromo-5-(4-methoxy-phenyl)-[1,3,4]thiadiazole 
• 59758-41-7 2-{[5-(4-methoxy-phenyl)-[1,3,4]thiadiazol-2-yl]-hydrazono}-propionic acid ethyl ester 
• 59758-36-0 2-hydrazino-5-(4-methoxy-phenyl)-[1,3,4]thiadiazole 
• 123-11-5 4-methoxy-benzaldehyde 
• 22278-81-5 4-amino-5-oxo-3-thioxo-6-methyl-2,3,4,5-tetrahydro<1,2,4>triazine 
• 100-09-4 4-methoxybenzoic acid 
• 22278-81-5 4-amino-6-methyl-3-thio-1,2,4-triazin-5-one 

Relevant articles and documents

Synthesis and biological studies of some new thiadiazolo [2,3-a] 1,2,4-triazin-5-ones

Treatment of thiocarbohydrazide 2 with pyruvic acid 1 in ethanol affords 4-amino-3-mercapto-6-methyl-1,2,4-triazin-5(4H)-one 3. Cyclization of 3 with various aromatic acids in presence of phosphorus oxychloride yields 2-substituted -6-methyI-4H-1,3,4-thiadiazolo [2,3-c], 1,2,4-triazin-5-ones (4a-j). The structures of the newly synthesized compounds have been established by means of IR, Mass, 1H NMR spectral data. All the new compounds (4a-j) were evaluated for their antibacterial and antifungal activities.

Synthesis and biological activity studies of 1,3,4-thiadiazolo[2,3-c]-as-triazines

Several new 1,3,4-thiadiazolo[2,3-c]-as-triazines were synthesized by the reaction of 6-substituted-4-amino-3-mercapto-1,3,4-triazon-5(4H)-ones with appropriate aromatic and heterocyclic carboxylic acids in the presence of phosphorus oxichloride. The structures of the newly synthesized compounds were established on the basis of analytical, IR, NMR and mass spectral data. Some selected compounds from this series were subjected to both antimicrobial and pharmacological studies.