43036-17-5

Basic information

• Product Name: 6-MeO-BTA-0
• Synonyms: Benzenamine, 4-(6-methoxy-2-benzothiazolyl)-
• CAS NO: 43036-17-5
• Molecular Formula: C₁₄H₁₂N₂OS
• Molecular Weight: 256.32
• Mol File: 43036-17-5.mol
• Article Data: 35

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-MeO-BTA-0(CAS DataBase Reference)
• NIST Chemistry Reference: 6-MeO-BTA-0(43036-17-5)
• EPA Substance Registry System: 6-MeO-BTA-0(43036-17-5)

Safety Data

• Hazardous Substances Data: 43036-17-5(Hazardous Substances Data)

Usage

Chemical Properties

Yellow solid

Upstream product

• 43036-14-2 6-methoxy-2-(4-nitrophenyl)benzothiazole 
• 2942-13-4 6-methoxy-1,3-benzothiazole 
• 106-40-1 4-bromo-aniline 
• 131818-17-2 tert-butyl (4-bromophenyl)carbamate 
• 24730-11-8 N-(4-methoxyphenyl)-4-nitrobenzamide 
• 73702-95-1 N-(4-methoxyphenyl)-4-nitrothiobenzamide 
• 104-94-9 4-methoxy-aniline 
• 122-04-3 4-nitro-benzoyl chloride 
• 150-13-0 4-amino-benzoic acid 
• 6274-29-9 2-amino-5-methoxy-thiophenol 
• 2941-58-4 2-bromo-6-methoxy-1,3 benzothiazole 
• 214360-73-3 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)aniline 
• 62-23-7 4-nitro-benzoic acid 
• 7732-36-7 bis(2-amino-5-methoxyphenyl)disulfide 

Downstream Products

• 178804-18-7 2-(4’-aminophenyl)-6-hydroxybenzothiazole 
• 178804-17-6 2-(4-amino-3-iodophenyl)-6-methoxybenzothiazole 
• 10205-71-7 4-(6-methoxybenzo[d]thiazol2-yl)-N,N-dimethylaniline 
• 247080-54-2 2-(4-amino-3-chlorophenyl)-6-methoxybenzothiazole 
• 247080-38-2 2-(4-amino-3-chloro-phenyl)-benzothiazol-6-ol 
• 401813-34-1 4-(6-methoxybenzo[d]thiazol-2-yl)-N-methylaniline 
• 1073610-35-1 4β-[4-(6-methoxy-1,3-benzothiazole-2-yl)anilino]-4-desoxypodophyllotoxin 
• 1073610-36-2 4'-O-demethyl-4β-[4-(6-methoxy-1,3-benzothiazole-2-yl)anilino]-4-desoxypodophyllotoxin 
• 1159301-83-3 2-(4’-chloroacetamide-phenyl)-6-methoxybenzothiazole 
• 1374349-54-8 N-[4-(6-methoxybenzo[d]thiazol-2-yl)phenyl]formamide 
• 1374349-45-7 N-[4-(6-methoxybenzo[d]thiazol-2-yl)phenyl]-N-(⁽¹¹⁾C-methyl)formamide 
• 1370531-54-6 N-[4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl]-1-cyclopropanecarboxamide 
• 1370531-52-4 N,N'-dicyclohexyl-N''-[4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl]guanidine 
• 1370531-53-5 N-benzyl-N'-[4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl]urea 

Relevant articles and documents

TARGETED ABERRANT ALPHA-SYNUCLEIN SPECIES AND INDUCED UBIQUITINATION AND PROTEOSOMAL CLEARANCE VIA CO-RECRUITMENT OF AN E3-LIGASE SYSTEM

Disclosed are bispecific compounds (degraders) that target α-synuclein protein for degradation. Also disclosed are pharmaceutical compositions containing the degraders and methods of using the compounds to treat neurodegenerative diseases.

Synthesis of 2-arylbenzothiazoles via direct condensation between in situ generated 2-aminothiophenol from disulfide cleavage and carboxylic acids

In this work we describe a simple and efficient general methodology for 2-arylbenzothiazole preparation employing disulfides and carboxylic acids. The reaction is promoted by tributylphosphine that acts both in disulfide bond cleavage and as activating agent for coupling with carboxylic acids. The reaction scope was studied using bis(2-aminophenyl)disulfide and different carboxylic acids with donor/withdrawing substituents, which resulted in the desired 2-arylbenzothiazole with moderate to good yields. The method was tested with success in preparation of the amyloid probe 2-(4-aminophenyl)-6-methoxybenzothiazole that employed a substituted bis(2-aminophenyl)disulfide.

2-Arylaminobenzothiazole-arylpropenone conjugates as tubulin polymerization inhibitors

A new series of 2-arylaminobenzothiazole-arylpropenone conjugates 5-6(a-r) was designed, synthesized and investigated for their cytotoxic potency against the various human cancer cell lines. Most of these conjugates exhibited cytotoxic activity and inhibi