43090-97-7 Usage
Description
1-[(4-nitrophenyl)sulfonyl]aziridine, also known as NPSA, is a chemical compound belonging to the class of aziridines. It features a three-membered ring with one nitrogen atom and two carbon atoms, along with a sulfonyl group and a nitrophenyl group attached to it. NPSA is recognized for its potential applications in organic synthesis, medicinal chemistry, and materials science due to its reactivity towards various nucleophiles and electrophiles, making it a versatile building block for complex molecule synthesis. Additionally, it has been studied for its potential biological activities, such as its role as an antitumor agent, and is valued by researchers for its unique structural features and reactivity.
Uses
Used in Organic Synthesis:
1-[(4-nitrophenyl)sulfonyl]aziridine is used as a versatile building block for the synthesis of complex molecules in organic synthesis. Its reactivity towards nucleophiles and electrophiles allows for the creation of a wide range of chemical compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-[(4-nitrophenyl)sulfonyl]aziridine is used as a key intermediate in the development of pharmaceuticals. Its unique structure and reactivity contribute to the design and synthesis of new drug candidates.
Used in Materials Science:
1-[(4-nitrophenyl)sulfonyl]aziridine is utilized as a component in the development of new materials in materials science. Its properties can be harnessed to create innovative materials with specific characteristics for various applications.
Used in Antitumor Research:
In the realm of antitumor research, 1-[(4-nitrophenyl)sulfonyl]aziridine is used as a potential antitumor agent. Its biological activities are being investigated for its potential role in combating cancer cells.
Used in Research:
1-[(4-nitrophenyl)sulfonyl]aziridine serves as a valuable tool for researchers in various fields of chemistry, including organic synthesis, medicinal chemistry, and materials science, due to its unique structural features and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 43090-97-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,3,0,9 and 0 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 43090-97:
(7*4)+(6*3)+(5*0)+(4*9)+(3*0)+(2*9)+(1*7)=107
107 % 10 = 7
So 43090-97-7 is a valid CAS Registry Number.
43090-97-7Relevant articles and documents
Well-Defined Poly(Ester Amide)-Based Homo- and Block Copolymers by One-Pot Organocatalytic Anionic Ring-Opening Copolymerization of N-Sulfonyl Aziridines and Cyclic Anhydrides
Xu, Jiaxi,Hadjichristidis, Nikos
, p. 6949 - 6954 (2021/03/01)
We report a new synthetic methodology for poly(ester amide)s by anionic ring-opening copolymerization of N-sulfonyl aziridines and cyclic anhydrides. Phosphazenes organocatalysts have been found to promote a highly-active, controlled, and selective altern
Synthesis of indolines: Via a palladium/norbornene-catalyzed reaction of aziridines with aryl iodides
Liu, Ce,Liang, Yujie,Zheng, Nian,Zhang, Bo-Sheng,Feng, Yuan,Bi, Siwei,Liang, Yong-Min
supporting information, p. 3407 - 3410 (2018/04/05)
A Pd- and norbornene-catalyzed domino procedure has been developed to synthesize indoline compounds. This reaction provides efficient access to indolines by employing aryl iodides with aziridines as new electrophiles. The transformation is scalable and tolerates a range of functional groups.
DIAZASPIROALKANEONE-SUBSTITUTED OXAZOLE DERIVATIVES AS SPLEEN TYROSINE KINASE INHIBITORS
-
, (2015/12/08)
The present invention is concerned with diazaspiroalkanone- substituted oxazole derivatives that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant protein kinases implicated in a variety of human a