43098-57-3

Basic information

• Product Name: 3-methyl-7-phenyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
• Synonyms: 3-methyl-7-phenyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
• CAS NO: 43098-57-3
• Molecular Formula: C₁₁H₈N₄OS
• Molecular Weight: 244.27242
• Mol File: 43098-57-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-methyl-7-phenyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-7-phenyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one(43098-57-3)
• EPA Substance Registry System: 3-methyl-7-phenyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one(43098-57-3)

Safety Data

• Hazardous Substances Data: 43098-57-3(Hazardous Substances Data)

Upstream product

• 22278-81-5 4-amino-5-oxo-3-thioxo-6-methyl-2,3,4,5-tetrahydro<1,2,4>triazine 
• 65-85-0 benzoic acid 
• 100-52-7 benzaldehyde 
• 22278-81-5 4-amino-6-methyl-3-thio-1,2,4-triazin-5-one 

Relevant articles and documents

Synthesis and biological studies of some new thiadiazolo [2,3-a] 1,2,4-triazin-5-ones

Treatment of thiocarbohydrazide 2 with pyruvic acid 1 in ethanol affords 4-amino-3-mercapto-6-methyl-1,2,4-triazin-5(4H)-one 3. Cyclization of 3 with various aromatic acids in presence of phosphorus oxychloride yields 2-substituted -6-methyI-4H-1,3,4-thiadiazolo [2,3-c], 1,2,4-triazin-5-ones (4a-j). The structures of the newly synthesized compounds have been established by means of IR, Mass, 1H NMR spectral data. All the new compounds (4a-j) were evaluated for their antibacterial and antifungal activities.

New synthesis of [1,3,4] thiadiazolo [2,3-c][1,2,4] triazinone; transfer of active electron by microwaves

Reaction of various aromatic aldehydes with 4-amino-6-methyl-1,2,4-triazin-5-one supported on to montmorillonite-K10 in the presence of nitrobenzene under microwaves irradiation, afforded the corresponding [1,3,4] thiadiazole [2,3-c][1,2,4]-triazinones.