431075-50-2

Basic information

• Product Name: Benzamide, N-[[(3-chloro-4-fluorophenyl)amino]thioxomethyl]-
• CAS NO: 431075-50-2
• Molecular Formula: C14H10ClFN2OS
• Molecular Weight: 308.764
• Mol File: 431075-50-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzamide, N-[[(3-chloro-4-fluorophenyl)amino]thioxomethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-[[(3-chloro-4-fluorophenyl)amino]thioxomethyl]-(431075-50-2)
• EPA Substance Registry System: Benzamide, N-[[(3-chloro-4-fluorophenyl)amino]thioxomethyl]-(431075-50-2)

Safety Data

• Hazardous Substances Data: 431075-50-2(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 367-21-5 3-chloro-4-fluorophenylamine 
• 532-55-8 Benzoyl isothiocyanate 

Downstream Products

• 1334511-26-0 1-benzoyl-3-(3'-chloro-4'-fluorophenyl)-4-methyl-1,3-dihydroimidazol-2-thione 
• 154371-25-2 1-(3-chloro-4-fluorophenyl)thiourea 

Relevant articles and documents

Synthesis and insecticidal activity of new substituted N-aryl-N′-benzoylthiourea compounds

Eight new substituted N -aryl- N ′-benzoylthioureas have been synthesised by a facile and mild method with high yield at room temperature. The structures of all compounds were confirmed by 1H NMR, mass and high resolution mass spectroscopy. The

Synthesis and antibacterial activity of new N-acyl-N′-(3-chloro-4- fluorophenyl)thioureas

A new series of N-acyl-N′-(3-chloro-4-fluorophenyl)thioureas have been prepared in excellent yield by the reaction of acylthiocyanates and 3-chloro-4-fluoroaniline under solid-liquid phase transfer catalysis using PEG-400. All synthesised compounds were screened against Escherichia coli and Staphylococcus aureus in DMF for evaluating their antibacterial activity. 2d, 2e, 2f and 2g showed good activity at 50 μg/ml dilution.