431079-79-7

Basic information

• Product Name: 1-tert-Butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate
• Synonyms: 1-tert-Butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate
• CAS NO: 431079-79-7
• Molecular Formula: C₁₁H₁₇NO₅
• Molecular Weight: 243
• Mol File: 431079-79-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 65-67 °C
• Boiling Point: 361.6±35.0 °C(Predicted)
• Appearance: /
• Density: 1.209±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 13.24±0.20(Predicted)
• CAS DataBase Reference: 1-tert-Butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-tert-Butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate(431079-79-7)
• EPA Substance Registry System: 1-tert-Butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate(431079-79-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 431079-79-7(Hazardous Substances Data)

Usage

General Description

1-tert-Butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate is a chemical compound with the molecular formula C14H21NO5. It is a tert-butyl ester of 3-methyl 2-oxopyrrolidine-1,3-dicarboxylic acid, commonly known as piracetam. 1-tert-Butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate is used as a cognitive enhancer and nootropic agent, and it is believed to improve memory, learning, and cognitive function. It is also used in the treatment of cognitive disorders and dementia. Its specific mechanism of action is not fully understood, but it is thought to modulate neurotransmitter levels in the brain, as well as enhance cerebral blood flow and glucose utilization. 1-tert-Butyl 3-methyl 2-oxopyrrolidine-1,3-dicarboxylate can be found in some dietary supplements and pharmaceutical preparations designed to improve cognitive function.

Upstream product

• 85909-08-6 tert-butyl 2-oxopyrrolidine-1-carboxylate 
• 79-22-1 methyl chloroformate 
• 616-45-5 2-pyrrolidinon 
• 24424-99-5 di-tert-butyl dicarbonate 
• 616-38-6 carbonic acid dimethyl ester 

Downstream Products

• 431079-83-3 4-{[but-3-ynyl-(toluene-4-sulfonyl)-amino]-methyl}-2,3-dihydro-pyrrole-1-carboxylic acid tert-butyl ester 
• 1039756-11-0 1-tert-butyl 3-methyl 2-oxo-3-((mesitylsulfonamido)ethyl)pyrrolidine-1,3-dicarboxylate 
• 1397496-03-5 1-tert-butyl 3-methyl 3-(3,4-dihydroxy-5-methoxyphenyl)-2-oxopyrrolidine-1,3-dicarboxylate 
• 1240791-69-8 tert-butyl 3-[benzyl(penta-3,4-dien-1-yl)carbamoyl]-2-oxopyrrolidine-1-carboxylate 
• 1397495-98-5 1-tert-butyl 3-methyl 3-(3,4-dihydroxyphenyl)-2-oxopyrrolidine-1,3-dicarboxylate 
• 1397496-01-3 1-tert-butyl 3-methyl 3-(3,4-dihydroxy-5-methylphenyl)-2-oxo-pyrrolidine-1,3-dicarboxylate 
• 1397496-06-8 C₁₈H₂₃NO₇ 

Relevant articles and documents

SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION

This invention provides compounds that have spirocyclic E3 Ubiquitin Ligase targeting moieties (Degrons), which can be used as is or linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation.

SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS

There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin and/or kallikrein, which compounds include substituted pyrazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which diseases or disorders are amenable to treatment or prevention by the inhibition of thrombin and/or kallikrein.

An oxidative coupling for the synthesis of arylated quaternary stereocentres and its application in the total synthesis of powelline and buphanidrine

Catechol derivatives directly bonded to all-carbon quaternary stereocentres are prevalent in nature. An oxidative coupling strategy for the synthesis of this motif is described. Pivoting on the base-catalysed Michael addition of carbon-centred pro-nucleop