4312-44-1

Basic information

• Product Name: 6-Hydroxy-4-quinolinecarboxylic acid
• Synonyms: 6-Hydroxy-4-quinolinecarboxylic acid;Xanthoquinic acid;6-hydroxyquinoline-4-carboxylic acid
• CAS NO: 4312-44-1
• Molecular Formula: C₁₀H₇NO₃
• Molecular Weight: 189.17
• Mol File: 4312-44-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 320 °C (decomp)
• Boiling Point: 426.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.480±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 1.12±0.30(Predicted)
• CAS DataBase Reference: 6-Hydroxy-4-quinolinecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Hydroxy-4-quinolinecarboxylic acid(4312-44-1)
• EPA Substance Registry System: 6-Hydroxy-4-quinolinecarboxylic acid(4312-44-1)

Safety Data

• Hazardous Substances Data: 4312-44-1(Hazardous Substances Data)

Usage

General Description

6-Hydroxy-4-quinolinecarboxylic acid, also known as 6-Hydroxy-4-quinolinecarboxylic acid or 4-Quinolinol-6-carboxylic acid, is an organic compound with the chemical formula C10H7NO3. It is a derivative of quinoline and contains a hydroxyl group and a carboxylic acid group on the quinoline ring. 6-Hydroxy-4-quinolinecarboxylic acid has been studied for its potential use in pharmaceuticals and has been found to exhibit antibacterial and antiviral properties. It has also been investigated for its ability to chelate metal ions and is used as a building block for the synthesis of various drug molecules. Additionally, 6-Hydroxy-4-quinolinecarboxylic acid has been utilized in the development of fluorescent probes for detecting metal ions in biological systems. Overall, this compound has significant potential for various applications in the pharmaceutical and chemical industries.

Upstream product

• 86-68-0 6-methoxyquinoline-4-carboxylic acid 

Downstream Products

• 580-16-5 6-hydroxyquinoline 
• 859780-30-6 6-hydroxy-quinoline-4-carbonyl chloride 
• 31610-09-0 Xanthochininsaeure-ethylester 
• 525-39-3 6-ethoxy-quinoline-4-carboxylic acid 

Relevant articles and documents

FIBROBLAST ACTIVATION PROTEIN LIGANDS FOR TARGETED DELIVERY APPLICATIONS

The present invention relates to ligands of Fibroblast Activation Protein (FAP) for the active delivery of various payloads (e.g. cytotoxic drugs, radionuclides, fluorophores, proteins and immunomodulators) at the site of disease. In particular, the prese

SPECT imaging agent for FAP-alpha specific tumor diagnosis

The invention relates to an SPECT imaging agent for FAP-alpha specific tumor diagnosis. The imaging agent is formed by taking a micromolecular FAP-alpha inhibitor of a modified N-4-quinolyl-glycine-(2S)-cyanoproline skeleton as a precursor compound, taking 99mTc as radionuclide and taking N-tris (hydroxymethyl) methylglycine (Tricine) and triphenylphosphine tri-m-sodium sulfonate (TPPTS) as synergistic ligands. Compared with the prior art, the imaging agent has high sensitivity, more excellent in-vivo biological distribution is shown, compared with the prior art, the complex has the advantagesof higher tumor uptake and tumor/organ uptake ratio, more stable coordination property, and excellent in-vivo and in-vitro stability. Due to the obvious coordination structure characteristics of theimaging agent, a one-step marking kit technology can be used, and the imaging agent has better druggability and is suitable for industrial production and clinical popularization.

Products arising in the performic oxidation of tryptophan.

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