4314-66-3

Basic information

• Product Name: N-ETHYLNICOTINAMIDE
• Synonyms: N-ETHYLNICOTINAMIDE;ethylnicotinamide,98%;n-ethyl-3-pyridinecarboxamid;n-ethyl-3-pyridinecarboxamide;n-ethyl-nicotinamid;nicotinicacidmonoethylamide;n-monoethylnicotinamide;N-ETHYLNICOTINAMIDE 98+%
• CAS NO: 4314-66-3
• Molecular Formula: C₈H₁₀N₂O
• Molecular Weight: 150.18
• EINECS: 224-331-7
• Product Categories: AMIDE
• Mol File: 4314-66-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 50 °C
• Boiling Point: 351.6°Cat760mmHg
• Flash Point: 166.4°C
• Appearance: /
• Density: 1.076g/cm³
• Vapor Pressure: 4.07E-05mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: N-ETHYLNICOTINAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-ETHYLNICOTINAMIDE(4314-66-3)
• EPA Substance Registry System: N-ETHYLNICOTINAMIDE(4314-66-3)

Safety Data

• RTECS: QS4471500
• Hazardous Substances Data: 4314-66-3(Hazardous Substances Data)

Usage

Description

N-Ethylnicotinamide, a derivative of Nicotinamide (N407750), is a water-soluble vitamin belonging to the vitamin B group. It possesses various biological activities and potential applications in different industries due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
N-Ethylnicotinamide is used as a pharmaceutical compound for its potential therapeutic effects. As a derivative of Nicotinamide, it may play a role in modulating cellular processes and could be utilized in the development of drugs targeting specific health conditions.
Used in Cosmetic Industry:
In the cosmetic industry, N-Ethylnicotinamide is used as an active ingredient for its potential benefits to skin health. It may contribute to improving skin texture, reducing the appearance of fine lines and wrinkles, and providing antioxidant protection.
Used in Research and Development:
N-Ethylnicotinamide is also used in research and development for its potential applications in various fields. Its unique chemical properties make it a valuable compound for studying biological processes and developing new therapeutic strategies.

InChI:InChI=1/C8H10N2O/c1-2-10-8(11)7-4-3-5-9-6-7/h3-6H,2H2,1H3,(H,10,11)

Upstream product

• 98-92-0 nicotinamide 
• 75-03-6 ethyl iodide 
• 20260-53-1 pyridine-3-carbonyl chloride hydrochloride 
• 75-04-7 ethylamine 
• 93-60-7 methyl 3-pyridinecarboxylate 
• 59-67-6 nicotinic acid 
• 61-54-1 tryptamine 

Downstream Products

• 500-22-1 3-pyridinecarboxaldehyde 
• 3000-75-7 N-ethyl-N-(3-pyridylmethyl)amine 
• 82352-78-1 C₂₄H₂₈N₄O₂⁽²⁺⁾*2Br^(1-) 
• 81388-58-1 C₂₄H₂₈N₄O₂⁽²⁺⁾*2Cl^(1-) 
• 82352-77-0 C₂₄H₂₈N₄O₂⁽²⁺⁾*2Br^(1-) 
• 78844-37-8 1,1'-p-xylylenebis<3-(N-ethylcarbamoyl)-1,4-dihydropyridine> 
• 82352-87-2 1,1'-m-xylylenebis<3-(N-ethylcarbamoyl)-1,4-dihydropyridine> 
• 82352-88-3 1,1'-o-xylylenebis<3-(N-ethylcarbamoyl)-1,4-dihydropyridine> 

Relevant articles and documents

Water soluble complexes of the antiviral drugs, 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine and acyclovir: The role of hydrophobicity in complex formation

We investigated water-soluble complexes of various ligands with the antiviral drugs, 9-[(2-hydroxyethoxy)methyl]guanine (acyclovir) and 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine (DHPG). For comparison, we also examined the 'parent' compounds, guanine and guanosine, as substrates for complex formation. Using the phase-solubility technique, we measured formation constant (K1) values at 23° C in pH 7 buffer. For a single substrate, formation constants with different ligands varied in the order: caffeine > pyridoxine ~~ cytidine > nicotinamide > sucrose. With caffeine as the ligand, formation constants with different substrates varied in the order: guanine > guanosine ~~ acyclovir > DHPG. The largest formation constant observed was 58 M-1 (for guanine-caffeine), and the smallest formation constant was 0.29 M-1 (for DHPG-sucrose). Examining the literature for formation constant data on compounds related to DHPB, and comparing literature data with our own, reveals a significant correlation between formation constants and ligand hydrophobicity. For 41 substrate-ligand pairs, least squares linear regression analysis of log K1 values versus various parameters reflecting donor-acceptor abilities (e.g., substrate and ligand HOMO and LUMO values, or substrate oxidation potentials) failed to significantly correlate. We conclude that ligand hydrophobicity is a general determinant of water soluble complex formation formation, but not necessarily the exclusive or dominant controlling factor for all complexes. Charge-transfer interactions are not important determinants of complex formation for the substrate-ligand combinations that we have considered.

Reactivity of biologically important reduced pyridines. 4. Effect of substitution on ferricyanide-mediated oxidation rates of various 1,4-dihydropyridines

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