43168-51-0

Basic information

• Product Name: 4-Epiminocycline
• Synonyms: Epiminocycline;[4R-(4a,4a,5a,12a)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydro-1,11-dioxo-2-naphthacenecarboxamide;4-Epi Minocycline (approximately 60% pure, contains unidentified salts);4-Epi Minocycline (>80%, contains unidentified salts);[4R-(4α,4aβ,5aβ,12aβ)]-4,7-Bis(diMethylaMino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydro-1,11-dioxo-2-naphthacenecarboxaMide;Minocycline EP IMpurity A;4-Epiminocycline;[4R-(4a,4ab,5ab,12ab)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydro-1,11-dioxo-2-naphthacenecarboxamide
• CAS NO: 43168-51-0
• Molecular Formula: C₂₃H₂₇N₃O₇
• Molecular Weight: 457.48
• Product Categories: Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Metabolite&impurity
• Mol File: 43168-51-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: >196°C (dec)
• Appearance: /
• Storage Temp.: Amber Vial, -20°C Freezer, Under Inert Atmosphere
• Solubility: Aquepus Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 4-Epiminocycline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Epiminocycline(43168-51-0)
• EPA Substance Registry System: 4-Epiminocycline(43168-51-0)

Safety Data

• Hazardous Substances Data: 43168-51-0(Hazardous Substances Data)

Usage

Description

4-Epiminocycline, also known as Minocycline EP Impurity A, is a chemical compound derived from the antibiotic Minocycline. It is characterized by its yellow-orange solid appearance. As an impurity, it is a byproduct in the synthesis process of Minocycline, which is a tetracycline antibiotic used to treat various bacterial infections.

Uses

Used in Pharmaceutical Industry:
4-Epiminocycline is used as an impurity in the production of Minocycline for the pharmaceutical industry. Its presence is important for quality control and regulatory compliance, as it can impact the efficacy and safety of the final drug product. The management and control of this impurity ensure that the Minocycline meets the required standards for therapeutic use.
Used in Research and Development:
In the field of research and development, 4-Epiminocycline serves as a valuable compound for studying the synthesis, properties, and potential applications of Minocycline and its derivatives. Understanding the characteristics and behavior of this impurity can contribute to the optimization of the manufacturing process and the development of new tetracycline-based antibiotics.
Used in Quality Control and Analysis:
4-Epiminocycline is used as a reference compound in the quality control and analysis of Minocycline products. It helps in the development and validation of analytical methods, such as high-performance liquid chromatography (HPLC) or other chromatographic techniques, to accurately quantify and identify impurities in the final drug product. This ensures the safety, efficacy, and consistency of Minocycline medications.
Used in Environmental and Industrial Applications:
Although not directly related to its pharmaceutical use, the chemical properties of 4-Epiminocycline, such as its yellow-orange solid appearance, may have potential applications in other industries, such as environmental monitoring or industrial processes. Further research and development could explore these possibilities and identify novel uses for this compound.