431988-79-3

Basic information

• Product Name: 5-(3-oxo-4-phenyl-butyl)-pyrrolidin-2-one
• Synonyms: 5-(3-oxo-4-phenyl-butyl)-pyrrolidin-2-one
• CAS NO: 431988-79-3
• Molecular Weight: 231.294
• Mol File: 431988-79-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(3-oxo-4-phenyl-butyl)-pyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-oxo-4-phenyl-butyl)-pyrrolidin-2-one(431988-79-3)
• EPA Substance Registry System: 5-(3-oxo-4-phenyl-butyl)-pyrrolidin-2-one(431988-79-3)

Safety Data

• Hazardous Substances Data: 431988-79-3(Hazardous Substances Data)

Upstream product

• 7766-86-1 3-(5-oxo-pyrrolidin-2-yl)-propionic acid 
• 91830-10-3 tetrahydro-pyrrolizine-3,5-dione 
• 6921-34-2 benzylmagnesium chloride 
• 18356-28-0 tetrahydro-pyrrolizin-3,5-dione 
• 1589-82-8 phenylmagnesium bromide 

Downstream Products

• 431988-80-6 5-(3-hydroxy-4-phenyl-butyl)-pyrrolidin-2-one 
• 431988-91-9 5-[4-(3-chloro-phenyl)-3-oxo-butyl]-pyrrolidin-2-one 
• 346673-04-9 5-[4-(4-fluoro-phenyl)-3-oxo-butyl]-pyrrolidin-2-one 
• 431988-78-2 4-{3-[2-(3-Hydroxy-4-phenyl-butyl)-5-oxo-pyrrolidin-1-yl]-propyl}-benzoic acid 
• 431988-81-7 5-[3-(tert-butyl-dimethyl-silanyloxy)-4-phenyl-butyl]-pyrrolidin-2-one 

Relevant articles and documents

Discovery of highly selective EP4 receptor agonists that stimulate new bone formation and restore bone mass in ovariectomized rats

Heptanoic acid lactams, exemplified by 2, were identified as highly selective EP4 agonists via high throughput screening. Lead optimization led to the identification of lactams with a 30-fold increase in EP4 potency in vitro. Compounds demonstrated robust