43214-88-6

Basic information

• Product Name: 5-Isoxazolemethanol,3-methyl-,acetate(ester)(9CI)
• Synonyms: 5-Isoxazolemethanol,3-methyl-,acetate(ester)(9CI);5-IsoxazoleMethanol,3-Methyl-, 5-acetate;3-Methyl-5-isoxazolemethanol acetate;(3-METHYL-1,2-OXAZOL-5-YL)METHYL ACETATE
• CAS NO: 43214-88-6
• Molecular Formula: C₇H₉NO₃
• Molecular Weight: 155.15
• EINECS: 200-258-5
• Product Categories: OXAZOLE
• Mol File: 43214-88-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 65-73℃ (2 Torr)
• Flash Point: 92.9±23.2℃
• Appearance: /
• Density: 1.153±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform, Methanol
• PKA: -1.87±0.10(Predicted)
• Stability: Moisture and Acid Sensitive
• CAS DataBase Reference: 5-Isoxazolemethanol,3-methyl-,acetate(ester)(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Isoxazolemethanol,3-methyl-,acetate(ester)(9CI)(43214-88-6)
• EPA Substance Registry System: 5-Isoxazolemethanol,3-methyl-,acetate(ester)(9CI)(43214-88-6)

Safety Data

• Hazardous Substances Data: 43214-88-6(Hazardous Substances Data)

Usage

Description

5-Isoxazolemethanol,3-methyl-,acetate(ester)(9CI) is an organic compound characterized by the presence of an isoxazole ring and a methyl group. It is an ester derivative of 3-methyl-5-isoxazolemethanol, where the hydroxyl group is esterified with acetic acid. 5-Isoxazolemethanol,3-methyl-,acetate(ester)(9CI) is known for its potential applications in various industries due to its unique chemical structure and properties.

Uses

Used in Pharmaceutical Industry:
5-Isoxazolemethanol,3-methyl-,acetate(ester)(9CI) is used as a pharmaceutical agent for its agonist characteristics relating to glutamic acid. It plays a crucial role in modulating the activity of glutamate receptors, which are involved in various physiological processes, including neurotransmission, memory, and learning. 5-Isoxazolemethanol,3-methyl-,acetate(ester)(9CI)'s agonist properties make it a promising candidate for the development of drugs targeting neurological disorders and conditions related to glutamate dysregulation.
Used in Chemical Research:
In the field of chemical research, 5-Isoxazolemethanol,3-methyl-,acetate(ester)(9CI) serves as a valuable compound for studying the structure-activity relationships of glutamate receptor agonists. Its unique chemical structure allows researchers to investigate the effects of modifications on the isoxazole ring and the methyl group on the compound's biological activity. This knowledge can be applied to design and synthesize novel compounds with improved pharmacological properties and potential therapeutic applications.
Used in Agrochemical Industry:
5-Isoxazolemethanol,3-methyl-,acetate(ester)(9CI) may also find applications in the agrochemical industry, where it could be utilized as a component in the development of novel pesticides or herbicides. Its agonist properties related to glutamic acid could potentially be exploited to target specific receptors in pests or weeds, providing a more selective and environmentally friendly approach to pest control.

Upstream product

• 40340-41-8 5-chloromethyl-3-methylisoxazole 
• 127-09-3 sodium acetate 

Downstream Products

• 1380089-51-9 (4-chlorophenyl)(2-(5-(hydroxymethyl)-3-methylisoxazol-4-yl)-4,5-dimethylthiophen-3-yl)methanone 
• 1380089-52-0 (R,E)-N-((4-(3-(4-chlorobenzoyl)-4,5-dimethylthiophen-2-yl)-3-methylisoxazol-5-yl)methylene)-2-methylpropane-2-sulfinamide 
• 1380089-53-1 (3R)-tert-butyl 3-(4-(3-(4-chlorobenzoyl)-4,5-dimethylthiophen-2yl)-3-methylisoxazol-5-yl)-3-((R)-1,1-dimethylethylsulfinamido)propanoate 
• 1380088-39-0 N-(((6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-isoxazolo[5,4-c]thieno[2,3-e]azepin-6-yl)methyl)acetamide 
• 1380088-40-3 methyl (((6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-isoxazolo[5,4-c]thieno[2,3-e]azepin-6-yl)methyl)carbamate 
• 1380090-23-2 (4-(3-(4-chlorobenzoyl)-1-methyl-1H-pyrazol-4-yl)-3-methylisoxazol-5-yl)methyl acetate 
• 1380090-24-3 4-chlorophenyl-(4-(5-(hydroxymethyl)-3-methylisoxazol-4-yl)-1-methyl-1H-pyrazol-3-yl)methanone . 
• 1380090-26-5 (4-(3-(4-chlorobenzoyl)-1-methyl-1H-pyrazol-4-yl)-3-methylisoxazol-5-yl)methyl methanesulfonate 
• 1380090-28-7 (4-(5-(azidomethyl)-3-methylisoxazol-4-yl)-1-methyl-1H-pyrazol-3-yl)(4-chlorophenyl)methanone 
• 1380089-17-7 6-(4-chlorophenyl)-1,8-dimethyl-4,8-dihydroisoxazolo[5,4-c]pyrazolo[4,3-e]azepine 
• 1448631-44-4 C₂₄H₂₅ClN₂O₃S 
• 1380087-45-5 2-((6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-isoxazolo[5,4-c]thieno[2,3-e]azepin-6-yl)acetamide 
• 1380088-19-6 2-((6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-isoxazolo[5,4-c]thieno[2,3-e]azepin-6-yl)-N-ethylacetamide 
• 1380089-76-8 2-((6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-isoxazolo[5,4-c]thieno[2,3-e]azepin-6-yl)ethanethioamide 

Relevant articles and documents

Reaction of 3-alkyl(aryl)-5-chloromethylisoxazoles with nucleophilic reagents

Previously unknown 3-alkyl(aryl)isoxazoles containing various functional groups in the 5-position were synthesized by reactions of 3-alkyl(aryl)-5- chloromethylisoxazoles with nucleophiles (2-aminoethanol, methylamine, sodium acetate, and sodium methoxide). Pleiades Publishing, Ltd., 2011.