433700-80-2

Basic information

• Product Name: 5,6-dimethyl-3-phenyl-2-(prop-2-yn-1-ylthio)thieno[2,3-d]pyrimidin-4(3H)-one
• Synonyms: 5,6-dimethyl-3-phenyl-2-(prop-2-yn-1-ylthio)thieno[2,3-d]pyrimidin-4(3H)-one
• CAS NO: 433700-80-2
• Molecular Weight: 326.443
• Mol File: 433700-80-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5,6-dimethyl-3-phenyl-2-(prop-2-yn-1-ylthio)thieno[2,3-d]pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-dimethyl-3-phenyl-2-(prop-2-yn-1-ylthio)thieno[2,3-d]pyrimidin-4(3H)-one(433700-80-2)
• EPA Substance Registry System: 5,6-dimethyl-3-phenyl-2-(prop-2-yn-1-ylthio)thieno[2,3-d]pyrimidin-4(3H)-one(433700-80-2)

Safety Data

• Hazardous Substances Data: 433700-80-2(Hazardous Substances Data)

Upstream product

• 59898-64-5 5,6-Dimethyl-3-phenyl-2-thioxo-2,3-dihydro-1H-thieno[2,3-d]pyrimidin-4-one 
• 106-96-7 propargyl bromide 

Downstream Products

• 512186-81-1 (8E)-8-(bromomethylidene)-2,3-dimethyl-4-oxo-5-phenyl-4,5,7,8-tetrahydro[1,3]-thiazolo[3,2-a]thieno[3,2-e]pyrimidin-9-ium bromide 

Relevant articles and documents

Stereoselective synthesis of (E)-halomethylidene[1,3]thiazolo[3,2-a] thieno[3,2-e] pyrimidinium and analogous [1,3]oxazolo[3,2-a] thieno[3,2-e]pyrimidinium halides starting from 3-N-substituted 2-propargylthio(oxy)thieno[2,3-d] pyrimidin-4-ones

A convenient procedure for the stereoselective synthesis of [1,3]thiazolo[3,2-a]thieno[3,2-e]pyrimidinium halides and analogous [1,3]oxazolo[3,2-a] thieno[3,2-e]pyrimidinium halides 5 and 6 is reported. 2-Propargylthio-3-R-thieno[2,3-d]pyrimidin-4-ones and 2-propargyloxy-3-R- thieno[2,3-d]pyrimidin-4-ones were treated with bromine or iodine in AcOH to afford (E)-halomethylidene[1,3]thiazolo[3,2-a]thieno[3,2-e]pyrimidinium and (E)-halomethylidene-[1,3]oxazolo[3,2-a]thieno[3,2-e] pyrimidinium halides, respectively.