4347-74-4 Usage
Description
[2-oxo-2-(4-phenylphenyl)ethyl] 4-methylbenzoate is a chemical compound categorized as an ester. It consists of a 4-methylbenzoate group connected to a [2-oxo-2-(4-phenylphenyl)ethyl] group. This white to off-white solid is sparingly soluble in water but readily dissolves in organic solvents, making it a versatile compound for various applications.
Uses
Used in Organic Synthesis:
[2-oxo-2-(4-phenylphenyl)ethyl] 4-methylbenzoate is used as a chemical intermediate in the field of organic synthesis for the production of various other compounds. Its unique structure allows it to serve as a building block in the creation of complex organic molecules.
Used in Fragrance Industry:
In the fragrance industry, [2-oxo-2-(4-phenylphenyl)ethyl] 4-methylbenzoate is used as a fragrance ingredient in perfumes and personal care products. Its aromatic properties contribute to the development of unique and pleasant scents, enhancing the sensory experience of these products.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, given its structural complexity and solubility in organic solvents, [2-oxo-2-(4-phenylphenyl)ethyl] 4-methylbenzoate could potentially be used in the pharmaceutical industry as a starting material for the synthesis of novel drug candidates or as a component in the formulation of existing medications.
Check Digit Verification of cas no
The CAS Registry Mumber 4347-74-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,4 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4347-74:
(6*4)+(5*3)+(4*4)+(3*7)+(2*7)+(1*4)=94
94 % 10 = 4
So 4347-74-4 is a valid CAS Registry Number.
InChI:InChI=1/C22H18O3/c1-16-7-9-20(10-8-16)22(24)25-15-21(23)19-13-11-18(12-14-19)17-5-3-2-4-6-17/h2-14H,15H2,1H3
4347-74-4Relevant articles and documents
Novel biphenyl ester derivatives as tyrosinase inhibitors: Synthesis, crystallographic, spectral analysis and molecular docking studies
Kwong, Huey Chong,Kumar, C. S. Chidan,Mah, Siau Hui,Chia, Tze Shyang,Quah, Ching Kheng,Loh, Zi Han,Chandraju, Siddegowda,Lim, Gin Keat
, (2017/03/09)
Biphenyl-based compounds are clinically important for the treatments of hypertension and inflammatory, while many more are under development for pharmaceutical uses. In the present study, a series of 2-([1,1'-biphenyl]-4-yl)-2-oxoethyl benzoates, 2(a-q), and 2-([1,1'- biphenyl]-4-yl)-2-oxoethyl pyridinecarboxylate, 2(r-s) were synthesized by reacting 1-([1,1'- biphenyl]-4-yl)-2-bromoethan-1-one with various carboxylic acids using potassium carbonate in dimethylformamide at ambient temperature. Single-crystal X-ray diffraction studies revealed a more closely packed crystal structure can be produced by introduction of biphenyl moiety. Five of the compounds among the reported series exhibited significant antityrosinase activities, in which 2p, 2r and 2s displayed good inhibitions which are comparable to standard inhibitor kojic acid at concentrations of 100 and 250 μg/mL. The inhibitory effects of these active compounds were further confirmed by computational molecular docking studies and the results revealed the primary binding site is active-site entrance instead of inner copper binding site which acted as the secondary binding site.
