4350-07-6

Basic information

• Product Name: D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID
• Synonyms: (2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propionic acid;(2R)-2-azanyl-3-(5-hydroxy-1H-indol-3-yl)propanoic acid;(R)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid;5-hydroxy-d-tryptopha;D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID;D-5-HTP;D-5-HYDROXYTRYPTOPHAN;(2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
• CAS NO: 4350-07-6
• Molecular Formula: C₁₁H₁₂N₂O₃
• Molecular Weight: 220.22
• EINECS: 224-411-1
• Mol File: 4350-07-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 270C
• Boiling Point: 520.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.484±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 2.22±0.10(Predicted)
• CAS DataBase Reference: D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID(4350-07-6)
• EPA Substance Registry System: D-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID(4350-07-6)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 20/21-20/21/22-36/37/38-65
• Safety Statements: 26-36
• Hazardous Substances Data: 4350-07-6(Hazardous Substances Data)

Usage

Definition

ChEBI: The D-enantiomer of 5-hydroxytryptophan.

InChI:InChI=1/C11H12N2O3/c12-9(11(15)16)5-7-3-6-4-8(14)1-2-10(6)13-7/h1-4,9,13-14H,5,12H2,(H,15,16)

Upstream product

• 3017-26-3 5-Benzyloxy-N^α-benzyloxycarbonyl-D-tryptophan 
• 93271-99-9 N-methoxycarbonyl-4-cyano-D-2-aminobutyric acid methyl ester 
• 93271-96-6 (R)-5-Hydroxy-pyrrolidine-1,2-dicarboxylic acid dimethyl ester 
• 93299-31-1 N-methoxycarbonyl-D-glutamine methyl ester 
• 89434-13-9 5-benzyloxy-N_b-methoxycarbonyl-D-tryptophan methyl ester 
• 93272-16-3 5-benzyloxy-N_b-methoxycarbonyl-D-tryptophan 
• 67010-10-0 N-acetyl-5-hydroxy-L-tryptophan 
• 83541-81-5 (S)-dimethyl pyrrolidine-1,2-dicarboxylate 
• 2311-25-3 N-acetyl-L-proline methyl ester 
• 53017-51-9 5-benzyloxy-N_b-acetyl-L-tryptophan 
• 53017-44-0 5-benzyloxy-N_b-acetyl-L-tryptophan methyl ester 
• 93271-98-8 N-methoxycarbonyl-4-cyano-L-2-aminobutyric acid methyl ester 
• 154005-67-1 (S)-1-Acetyl-5-hydroxy-pyrrolidine-2-carboxylic acid methyl ester 
• 93271-96-6 (2S,5RS)-1,2-dimethyl-5-hydroxypyrrolidine-1,2-dicarboxylate 

Downstream Products

• 84658-37-7 hyrtioerectine C 

Relevant articles and documents

Syntheses of Substituted L- and D-Tryptophans

Several 5-substituted nb-methoxycarbonyl-L- and -D-tryptophan derivatives were synthesized from proline by a new route involving electrochemical oxidation, as well as by the known procedures.Removal of the Nb-methoxycarbonyl group was accomplished by treatment with Me3SiI in refluxing chloroform, then alkaline hydrolysis of the methyl esters afforded 5-substituted L- and D-tryptophans with high optical purities.Keywords - L-tryptophan 5-substituted; D-tryptophan 5-substituted; anodic oxidation; N-methoxycarbonyl group deprotection; Fischer indole synthesis; iodotrimethylsilane