435271-24-2

Basic information

• Product Name: 3-Pyridinecarbonitrile,4-(dimethylamino)-
• Synonyms: 3-Pyridinecarbonitrile,4-(dimethylamino)-;3-Pyridinecarbonitrile,4-(dimethylamino)-(9CI)
• CAS NO: 435271-24-2
• Molecular Formula: C₈H₉N₃
• Molecular Weight: 147.17716
• Product Categories: PYRIDINE;AMINETERTIARY
• Mol File: 435271-24-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Pyridinecarbonitrile,4-(dimethylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonitrile,4-(dimethylamino)-(435271-24-2)
• EPA Substance Registry System: 3-Pyridinecarbonitrile,4-(dimethylamino)-(435271-24-2)

Safety Data

• Hazardous Substances Data: 435271-24-2(Hazardous Substances Data)

Upstream product

• 19158-51-1 P-toluenesulfonyl cyanide 
• 84539-35-5 (3-bromopyridin-4-yl)-dimethyl-amine 
• 154237-70-4 4-bromopyridine-3-carbonitrile 
• 124-40-3 dimethyl amine 

Relevant articles and documents

PYRAZINE COMPOUNDS AND USES THEREOF

The present disclosure novel pyrazine compounds targeting adenosine receptors (especially A1 and A2, particularly A2a). The present disclosure also relates to pharmaceutical compositions comprising one or more of the compounds as an active ingredient, and use of the compounds in the treatment of adenosine receptor (AR) associated diseases, for example cancer such as NSCLC, RCC, prostate cancer, and breast cancer.

SUBSTITUTED THIAZOLE DERIVATIVES BEARING 3-PYRIDYL GROUPS, PROCESS FOR PREPARING THE SAME AND USE THEREOF

The present invention provides a pharmaceutical composition having a steroid C17,20-lyase inhibitory activity, which is useful as a prophylactic or therapeutic agent of prostatism, tumor such as breast cancer and the like, more particularly, a steroid C17,20-lyase inhibitor containing a compound represented by the formula: wherein A1 is an aromatic hydrocarbon group optionally having substituents or a heterocyclic group optionally having substituents, one of A2 and A3 is a hydrogen atom, a halogen atom, a C1-4 aliphatic hydrocarbon group optionally having substituents or an optionally esterified carboxyl group, the other of A2 and A3 is an aromatic hydrocarbon group optionally having substituents or a heterocyclic group optionally having substituents, and at least one of A1, A2 and A3 is a 3-pyridyl group optionally having substituents, or a salt thereof or a prodrug thereof.