4364-76-5Relevant articles and documents
Acylation of guanylhydrazones derived from cyclic ketones: Synthesis of 3-acylamino-1-cycloalkenyl-5-methyl-1H-1,2,4-triazoles
Gy?rgydeák, Zoltan,Holzer, Wolfgang
, p. 1395 - 1406 (1998)
Reaction of guanylhydrazones derived from different cycloalkanones, 1-indanone and 4-chromanone, respectively, with excessive acetic anhydride leads to the formation of 3-acetylamino-1-cycloalkenyl-5-methyl-1H-1,2,4-triazoles. However, with camphor guanylhydrazone only the corresponding N,N'-diacetyl-guanylhydrazone was obtained, whereas 2-adamantone guanylhydrazone afforded 2-(3-acetylamino-5-methyl-1,2,4-triazol-1-yl)-2-adamantyl acetate. Detailed NMR spectroscopic studies (1H, 13C) with the title compounds and their guanylhydrazone precursors are presented.